The complex pathogenesis of inflammatory bowel disease (IBD) explains the several
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …

The P2X7 receptor is a trimeric ligand-gated cation channel activated by extracellular
adenosine 5′-triphosphate. The study of animals has greatly advanced the investigation of …

Allogeneic hematopoietic stem cell transplantation is used to treat blood cancers, but often
results in lethal graft-versus-host disease (GVHD). GVHD is an inflammatory disorder …

Aims Application of exogenous nucleotides can modulate wound healing via the activation
of purinergic receptors. However, evidence for the release of endogenous nucleotides and …

Graft‐versus‐host disease (GVHD) is a life‐threatening complication following donor
hematopoietic stem cell transplantation, where donor T cells damage host tissues. This …

Graft-versus-host disease (GVHD) is a T cell-mediated inflammatory disorder that arises
from allogeneic haematopoietic stem cell transplantation and is often fatal. The P2X7 …

Graft-versus-host disease (GVHD) is a severe inflammatory response arising from
allogeneic haematopoietic stem cell transplantation. Previous studies revealed that …

The therapeutic efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is
limited by the development of graft-versus-host disease (GVHD). In GVHD, rigorous pre …

Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for
blood cancers and other haematological disorders. However, allo-HSCT leads to graft …

The P2X7 receptor is an ion channel gated by the nucleotide ATP, known for its role in
immune responses and recently emerging as a critical onco-promoting factor. Lymphocytes …