[HTML][HTML] Antibiotics needed to treat multidrug-resistant infections in neonates

PCM Williams, SA Qazi, R Agarwal… - Bulletin of the World …, 2022 - ncbi.nlm.nih.gov
Despite a significant decline in deaths in children younger than 5 years globally in the past
three decades, preventable and treatable infectious diseases remain the leading cause of …

Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019

KS Ikuta, LR Swetschinski, GR Aguilar, F Sharara… - The Lancet, 2022 - thelancet.com
Background Reducing the burden of death due to infection is an urgent global public health
priority. Previous studies have estimated the number of deaths associated with drug …

Prevalence of gram-negative bacteria and their antibiotic resistance in neonatal sepsis in Iran: a systematic review and meta-analysis

N Moftian, P Rezaei-Hachesu, M Arab-Zozani… - BMC Infectious …, 2023 - Springer
Background Neonatal sepsis, particularly gram-negative (GN) bacteria-induced, is a
significant cause of morbidity and mortality in newborns. Healthcare professionals find this …

Patterns of antibiotic use, pathogens, and prediction of mortality in hospitalized neonates and young infants with sepsis: A global neonatal sepsis observational cohort …

NJ Russell, W Stöhr, N Plakkal, A Cook… - PLoS …, 2023 - journals.plos.org
Background There is limited data on antibiotic treatment in hospitalized neonates in low-and
middle-income countries (LMICs). We aimed to describe patterns of antibiotic use …

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Y Chen, J Cai, D Liu, S Liu, D Lei… - Regenerative …, 2022 - academic.oup.com
The synergistic effect of antibacterial and anti-inflammatory is needed to overcome the
problem of wound healing difficulties. Based on the favorable antibacterial and anti …

Global, regional, and national estimates of the impact of a maternal Klebsiella pneumoniae vaccine: A Bayesian modeling analysis

CK Kumar, K Sands, TR Walsh, S O'Brien… - PLoS …, 2023 - journals.plos.org
Background Despite significant global progress in reducing neonatal mortality, bacterial
sepsis remains a major cause of neonatal deaths. Klebsiella pneumoniae (K. pneumoniae) …

Prevalence and clonal diversity of carbapenem-resistant Klebsiella pneumoniae causing neonatal infections: A systematic review of 128 articles across 30 countries

Y Hu, Y Yang, Y Feng, Q Fang, C Wang, F Zhao… - PLoS …, 2023 - journals.plos.org
Background Klebsiella pneumoniae is the most common pathogen causing neonatal
infections, leading to high mortality worldwide. Along with increasing antimicrobial use in …

Antibiotic susceptibility of Escherichia coli isolated from neonates admitted to neonatal intensive care units across China from 2015 to 2020

R Xiao, Y Li, X Liu, Y Ding, J Lai, Y Li… - Frontiers in cellular …, 2023 - frontiersin.org
Background Escherichia coli is one of the most common pathogens causing neonatal
infections. Recently, the incidence and drug resistance of E. coli have increased, posing a …

Neonatal bacterial sepsis

T Strunk, EJ Molloy, A Mishra, ZA Bhutta - The Lancet, 2024 - thelancet.com
Neonatal sepsis remains one of the key challenges of neonatal medicine, and together with
preterm birth, causes almost 50% of all deaths globally for children younger than 5 years …

Phenotypic and genotypic antibiotic susceptibility profiles of Gram-negative bacteria isolated from bloodstream infections at a referral hospital, Lusaka, Zambia

K Yamba, C Lukwesa-Musyani… - PLOS Global Public …, 2023 - journals.plos.org
Bloodstream infections (BSI) caused by antimicrobial-resistant (AMR) Gram-negative
bacteria (GNB) are a significant cause of morbidity and mortality. Third-generation …