The evolving role of liquid biopsy in lung cancer
Liquid biopsy has revolutionized the management of cancer patients. In particular, liquid
biopsy-based testing has proven to be highly beneficial for identifying actionable cancer …
biopsy-based testing has proven to be highly beneficial for identifying actionable cancer …
Nanomedicine combats drug resistance in lung cancer
Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …
[HTML][HTML] Tyrosine kinase receptors in oncology
J Esteban-Villarrubia, JJ Soto-Castillo, J Pozas… - International journal of …, 2020 - mdpi.com
Tyrosine kinase receptors (TKR) comprise more than 60 molecules that play an essential
role in the molecular pathways, leading to cell survival and differentiation. Consequently …
role in the molecular pathways, leading to cell survival and differentiation. Consequently …
Phase I study of 2-or 3-week dosing of telisotuzumab vedotin, an antibody–drug conjugate targeting c-Met, monotherapy in patients with advanced non–small cell lung …
DR Camidge, D Morgensztern, RS Heist, M Barve… - Clinical Cancer …, 2021 - AACR
Abstract Purpose: Telisotuzumab vedotin (Teliso-V) is an anti–c-Met–directed antibody–drug
conjugate. Here, we present safety and efficacy data from a phase I/Ib study of Teliso-V …
conjugate. Here, we present safety and efficacy data from a phase I/Ib study of Teliso-V …
[HTML][HTML] Lung cancer in Republic of China
YH Luo, CH Chiu, CHS Kuo, TY Chou, YC Yeh… - Journal of Thoracic …, 2021 - Elsevier
Located in the west Pacific between Japan and the Philippines, the Republic of China has a
population of more than 23 million people. Malignant tumors are the leading cause of death …
population of more than 23 million people. Malignant tumors are the leading cause of death …
[HTML][HTML] Immunotherapy in Non-Small Cell Lung Cancer With Actionable Mutations Other Than EGFR
K Seegobin, U Majeed, N Wiest, R Manochakian… - Frontiers in …, 2021 - frontiersin.org
While first line targeted therapies are the current standard of care treatment for non-small
cell lung cancer (NSCLC) with actionable mutations, the cancer cells inevitably acquire …
cell lung cancer (NSCLC) with actionable mutations, the cancer cells inevitably acquire …
Targeted therapy for lung cancer: Beyond EGFR and ALK
M Herrera‐Juárez, C Serrano‐Gómez… - Cancer, 2023 - Wiley Online Library
Precision oncology comprises the set of strategies that aim to design the best cancer
treatment based on tumor biology. A recognized subset of patients with non‐small cell lung …
treatment based on tumor biology. A recognized subset of patients with non‐small cell lung …
[HTML][HTML] Foretinib can overcome common on-target resistance mutations after capmatinib/tepotinib treatment in NSCLCs with MET exon 14 skipping mutation
T Fujino, K Suda, T Koga, A Hamada, S Ohara… - Journal of Hematology & …, 2022 - Springer
Background Capmatinib and tepotinib are guideline-recommended front-line treatments for
non-small-cell lung cancer (NSCLC) patients with MET exon 14 skipping mutations …
non-small-cell lung cancer (NSCLC) patients with MET exon 14 skipping mutations …
The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer
B Melosky, P Wheatley-Price, RA Juergens, A Sacher… - Lung Cancer, 2021 - Elsevier
Lung cancer is a highly heterogeneous disease often driven by well-characterized driver
mutations. Although the best studied are common alterations in the epidermal growth factor …
mutations. Although the best studied are common alterations in the epidermal growth factor …
Cancer drug approvals that displaced existing standard-of-care therapies, 2016-2021
Importance Although several cancer drugs receive US Food and Drug Administration (FDA)
approval each month, it is unclear how many of these cancer drugs transform the treatment …
approval each month, it is unclear how many of these cancer drugs transform the treatment …