Chronic diabetic wounds and their treatment with skin substitutes

J Holl, C Kowalewski, Z Zimek, P Fiedor, A Kaminski… - Cells, 2021 - mdpi.com
With the global prevalence of type 2 diabetes mellitus steeply rising, instances of chronic,
hard-healing, or non-healing diabetic wounds and ulcers are predicted to increase. The …

Why traditional herbal medicine promotes wound healing: Research from immune response, wound microbiome to controlled delivery

Z Xu, M Dong, S Yin, J Dong, M Zhang, R Tian… - Advanced Drug Delivery …, 2023 - Elsevier
Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …

Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation

Y Guan, H Niu, Z Liu, Y Dang, J Shen, M Zayed… - Science …, 2021 - science.org
Nonhealing diabetic wounds are common complications for diabetic patients. Because
chronic hypoxia prominently delays wound healing, sustained oxygenation to alleviate …

Mechano‐activated cell therapy for accelerated diabetic wound healing

Y Shou, Z Le, HS Cheng, Q Liu, YZ Ng… - Advanced …, 2023 - Wiley Online Library
Chronic diabetic wounds are a significant global healthcare challenge. Current strategies,
such as biomaterials, cell therapies, and medical devices, however, only target a few …

Stimuli-responsive therapeutic systems for the treatment of diabetic infected wounds

Y Hu, H Li, X Lv, Y Xu, Y Xie, L Yuwen, Y Song, S Li… - Nanoscale, 2022 - pubs.rsc.org
Diabetic wound infection is a common disease that has significantly reduced people's
quality of life. Although tremendous achievements have been made in clinical treatment, the …

Antimicrobial peptides: challenging journey to the pharmaceutical, biomedical, and cosmeceutical use

A Mazurkiewicz-Pisarek, J Baran, T Ciach - International journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs), or host defence peptides, are short proteins in various life
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …

Biomimetic bilayered scaffolds for tissue engineering: from current design strategies to medical applications

C Bertsch, H Maréchal, V Gribova… - Advanced …, 2023 - Wiley Online Library
Tissue damage due to cancer, congenital anomalies, and injuries needs new efficient
treatments that allow tissue regeneration. In this context, tissue engineering shows a great …

The insights of microbes' roles in wound healing: A comprehensive review

T Maheswary, AA Nurul, MB Fauzi - Pharmaceutics, 2021 - mdpi.com
A diverse range of normal flora populates the human skin and numbers are relatively
different between individuals and parts of the skin. Humans and normal flora have formed a …

Biopolymers in diabetic wound care management: A potential substitute to traditional dressings

S Hasan, MA Hasan, MU Hassan, M Amin… - European Polymer …, 2023 - Elsevier
The poor healing of diabetic wound affects large proportion of human beings by high
mortality rate and associated expenditures. Such chronic wounds mainly become …

Diabetic ferroptosis plays an important role in triggering on inflammation in diabetic wound

S Li, Y Li, Z Wu, Z Wu, H Fang - American Journal of …, 2021 - journals.physiology.org
Impaired wound healing is a major complication of diabetes and involves sustained
inflammation and oxidative stress at the wound site. Here, we investigated the potential …