Diabetes, metabolic syndrome and dyslipidemia in people living with HIV in Africa: re-emerging challenges not to be forgotten

NE Husain, SK Noor, WM Elmadhoun… - HIV/AIDS-Research …, 2017 - Taylor & Francis
Background The current challenge in managing people living with human immunodeficiency
virus (PLWHIV) includes the identification and monitoring for comorbid health risks …

The CCL2/CCR2 axis in the pathogenesis of HIV-1 infection: a new cellular target for therapy?

D Angela Covino, M Sabbatucci… - Current drug targets, 2016 - ingentaconnect.com
The identification of chemokine receptors as necessary co-receptors for HIV entry into target
cells represented a breakthrough in the understanding of the pathogenesis of this viral …

Endocrinological aspects of HIV infection

FS Mirza, P Luthra, L Chirch - Journal of Endocrinological Investigation, 2018 - Springer
Purpose Patients with human immunodeficiency virus (HIV) are living longer with effective
antiretroviral therapies and are enjoying near normal life span. Therefore, they are …

HIV, vascular risk factors, and cognition in the combination antiretroviral therapy era: a systematic review and meta-analysis

EC McIntosh, K Tureson, LJ Rotblatt… - Journal of the …, 2021 - cambridge.org
Objectives: Mounting evidence indicates that vascular risk factors (VRFs) are elevated in HIV
and play a significant role in the development and persistence of HIV-associated …

Clinical Pharmacokinetics of the Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor Doravirine: An Assessment of the Effect of Patient Characteristics and …

S Khalilieh, KL Yee, R Sanchez, SA Stoch… - Clinical Drug …, 2020 - Springer
Abstract Doravirine (MK-1439) is a novel non-nucleoside reverse transcriptase inhibitor
indicated for the combination treatment of human immunodeficiency virus type-1 (HIV-1) …

Prevalence and Factors Associated with Dyslipidemia Among People Living with HIV/AIDS on Follow-Up Care at a Tertiary Care Hospital in Ethiopia: A Cross …

A Assefa, AA Abiye, TA Tadesse… - Drug, Healthcare and …, 2023 - Taylor & Francis
Background Despite its importance as a major risk factor for cardiovascular disease,
dyslipidemia remains poorly characterized in the African population. Objective To assess the …

Results of a doravirine-atorvastatin drug-drug interaction study

S Khalilieh, KL Yee, RI Sanchez… - Antimicrobial Agents …, 2017 - Am Soc Microbiol
Doravirine is a novel, highly potent, nonnucleoside reverse transcriptase inhibitor that is
administered once daily and that is in development for the treatment of HIV-1 infection. In …

Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy

N Tarantino, F Santoro, L De Gennaro… - Vascular health and …, 2017 - Taylor & Francis
Lipids disorder is the principal cause of atherosclerosis and may present with several forms,
according to blood lipoprotein prevalence. One of the most common forms is combined …

Inhibition of CYP2B6 by medicinal plant extracts: implication for use of efavirenz and nevirapine-based highly active anti-retroviral therapy (HAART) in resource-limited …

NE Thomford, C Awortwe, K Dzobo, F Adu, D Chopera… - Molecules, 2016 - mdpi.com
Highly active antiretroviral therapy (HAART) has greatly improved health parameters of HIV
infected individuals. However, there are several challenges associated with the chronic …

[HTML][HTML] Changes in lipid indices in HIV+ cases on HAART

S Ji, Y Xu, D Han, X Peng, X Lu… - BioMed Research …, 2019 - hindawi.com
We assess long-term changes in lipid levels in human immunodeficiency disease-(HIV-)
infected patients undergoing highly active antiretroviral treatment (HAART) and their …