[HTML][HTML] Antimicrobial peptides: an update on classifications and databases
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …
indispensable component of host defenses. They consist of predominantly short cationic …
Staphylococcus aureus and atopic dermatitis: a complex and evolving relationship
Staphylococcus aureus is frequently isolated from the skin of atopic dermatitis (AD) patients
during flares. The normal microbiota is disrupted and the diversity of the microorganisms on …
during flares. The normal microbiota is disrupted and the diversity of the microorganisms on …
[HTML][HTML] Therapeutic potential of bacteriophage endolysins for infections caused by Gram-positive bacteria
H Liu, Z Hu, M Li, Y Yang, S Lu, X Rao - Journal of biomedical science, 2023 - Springer
Abstract Gram-positive (G+) bacterial infection is a great burden to both healthcare and
community medical resources. As a result of the increasing prevalence of multidrug-resistant …
community medical resources. As a result of the increasing prevalence of multidrug-resistant …
Alternatives to antibiotics—a pipeline portfolio review
L Czaplewski, R Bax, M Clokie, M Dawson… - The Lancet infectious …, 2016 - thelancet.com
Antibiotics have saved countless lives and enabled the development of modern medicine
over the past 70 years. However, it is clear that the success of antibiotics might only have …
over the past 70 years. However, it is clear that the success of antibiotics might only have …
[HTML][HTML] The global threat of antimicrobial resistance: science for intervention
In the last decade we have witnessed a dramatic increase in the proportion and absolute
number of bacterial pathogens resistant to multiple antibacterial agents. Multidrug-resistant …
number of bacterial pathogens resistant to multiple antibacterial agents. Multidrug-resistant …
[HTML][HTML] Phage-encoded endolysins
F Abdelrahman, M Easwaran, OI Daramola, S Ragab… - Antibiotics, 2021 - mdpi.com
Due to the global emergence of antibiotic resistance, there has been an increase in
research surrounding endolysins as an alternative therapeutic. Endolysins are phage …
research surrounding endolysins as an alternative therapeutic. Endolysins are phage …
[HTML][HTML] Non-traditional antibacterial therapeutic options and challenges
U Theuretzbacher, LJV Piddock - Cell host & microbe, 2019 - cell.com
The global challenges presented by drug-resistant bacterial infections have stimulated much
activity in finding new treatments. This review summarizes the progress and setbacks of non …
activity in finding new treatments. This review summarizes the progress and setbacks of non …
Engineered endolysin-based “Artilysins” to combat multidrug-resistant gram-negative pathogens
Y Briers, M Walmagh, V Van Puyenbroeck… - MBio, 2014 - Am Soc Microbiol
The global threat to public health posed by emerging multidrug-resistant bacteria in the past
few years necessitates the development of novel approaches to combat bacterial infections …
few years necessitates the development of novel approaches to combat bacterial infections …
[HTML][HTML] Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era
H Ling, X Lou, Q Luo, Z He, M Sun, J Sun - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Antibiotic resistance is one of the biggest threats to global health, as it can make the
treatment of bacterial infections in humans difficult owing to their high incidence rate …
treatment of bacterial infections in humans difficult owing to their high incidence rate …
[HTML][HTML] Enzymes and mechanisms employed by tailed bacteriophages to breach the bacterial cell barriers
S Fernandes, C São-José - Viruses, 2018 - mdpi.com
Monoderm bacteria possess a cell envelope made of a cytoplasmic membrane and a cell
wall, whereas diderm bacteria have and extra lipid layer, the outer membrane, covering the …
wall, whereas diderm bacteria have and extra lipid layer, the outer membrane, covering the …