Mismatch repair

R Fishel, JB Lee - … , and Repair: Molecular Mechanisms and Pathology, 2016 - Springer
The concept of mismatch repair (MMR) was formulated independently in 1964 to explain the
removal of brominated nucleotides from DNA as well as gene conversion during genetic …

N6‐methyladenine: the other methylated base of DNA

D Ratel, JL Ravanat, F Berger, D Wion - Bioessays, 2006 - Wiley Online Library
Contrary to mammalian DNA, which is thought to contain only 5‐methylcytosine (m5C),
bacterial DNA contains two additional methylated bases, namely N6‐methyladenine (m6A) …

Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications

MJ Koziol, CR Bradshaw, GE Allen… - Nature structural & …, 2016 - nature.com
Methylation of cytosine deoxynucleotides generates 5-methylcytosine (m5dC), a well-
established epigenetic mark. However, in higher eukaryotes much less is known about …

Initiation of methyl-directed mismatch repair.

KG Au, K Welsh, P Modrich - Journal of Biological Chemistry, 1992 - ASBMB
Escherichia coli MutH possesses an extremely weak d (GATC) endonuclease that responds
to the state of methylation of the sequence (Welsh, KM, Lu, A.-L., Clark, S., and Modrich …

[PDF][PDF] Sulfur metabolism in Escherichia coli and related bacteria: facts and fiction

A Sekowska, HF Kung, A Danchin - Journal of molecular microbiology …, 2000 - caister.com
Living organisms are composed of macromolecules made of hydrogen, carbon, nitrogen,
oxygen, phosphorus and sulfur. Much work has been devoted to the metabolism of the first …

[HTML][HTML] MutS mediates heteroduplex loop formation by a translocation mechanism

DJ Allen, A Makhov, M Grilley, J Taylor… - The EMBO …, 1997 - embopress.org
Interaction of Escherichia coli MutS and MutL with heteroduplex DNA has been visualized
by electron microscopy. In a reaction dependent on ATP hydrolysis, complexes between a …

Advances in mapping the epigenetic modifications of 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4‐methylcytosine (4mC)

H Lv, FY Dao, D Zhang, H Yang… - Biotechnology and …, 2021 - Wiley Online Library
DNA modification plays a pivotal role in regulating gene expression in cell development. As
prevalent markers on DNA, 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4 …

Methyl-directed DNA mismatch correction

P Modrich - Journal of Biological Chemistry, 1989 - Elsevier
In 1964 Robin Holliday (1) proposed the correction of DNA base pair mismatches within
recombination intermediates as the basis for gene conversion. The existence of the …

Method for creating polynucleotide and polypeptide sequences

F Arnold, Z Shao, A Volkov - US Patent 6,537,746, 2003 - Google Patents
4,994,368 A 2/1991 Goodman et al. 4,994,379 A* 2/1991 Chang....................... 435/69.1
5,023,171. A 6/1991 Ho et al. 5,043,272 A 8/1991 Hartley 5,093.257 A 3/1992 Gray …

[HTML][HTML] Isolation and characterization of the Escherichia coli mutH gene product.

KM Welsh, AL Lu, S Clark, P Modrich - Journal of Biological Chemistry, 1987 - Elsevier
The Escherichia coli mutH gene product has been isolated in near homogeneous form using
an in vitro complementation assay for DNA mismatch correction (Lu, A.-L., Clark, S., and …