Recent developments in functionalized polymer nanoparticles for efficient drug delivery system

S Sur, A Rathore, V Dave, KR Reddy… - Nano-Structures & Nano …, 2019 - Elsevier
To overcome the shortcomings of conventional dosage forms, targeted and modified drug
delivery system came into existence. This was the time when a novel drug delivery system …

Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems

MT Luiz, JSR Viegas, JP Abriata, F Viegas… - European Journal of …, 2021 - Elsevier
Nanotechnology has been widely applied to develop drug delivery systems to improve
therapeutic performance. The effectiveness of these systems is intrinsically related to their …

Optimization to development of chitosan decorated polycaprolactone nanoparticles for improved ocular delivery of dorzolamide: In vitro, ex vivo and toxicity …

MS Shahab, M Rizwanullah, S Alshehri… - International journal of …, 2020 - Elsevier
The present research work was designed to develop dorzolamide-loaded chitosan-coated
polycaprolactone nanoparticles (DRZ-CS-PCL-NPs) for improved ocular delivery. The …

Polymeric versus lipid nanocapsules for miconazole nitrate enhanced topical delivery: in vitro and ex vivo evaluation

RS Abdel-Rashid, DA Helal, AA Alaa-Eldin… - Drug Delivery, 2022 - Taylor & Francis
Nanocapsules can be equated to other nanovesicular systems in which a drug is entrapped
in a void containing liquid core surrounded by a coat. The objective of the present study was …

Process optimization by response surface methodology for preparation and evaluation of methotrexate loaded chitosan nanoparticles

NR Naveen, M Kurakula, B Gowthami - Materials Today: Proceedings, 2020 - Elsevier
Abstract Formulation optimization is a critical process in the development of nanoparticles to
apprehend the formulation variables and associated quality attributes. Nanoparticles …

Preparation of phthalocyanine green nano pigment using supercritical CO2 gas antisolvent (GAS): experimental and modeling

NS Ardestani, G Sodeifian, SA Sajadian - Heliyon, 2020 - cell.com
Phthalocyanine green nano pigment was prepared using supercritical gas antisolvent (GAS)
process based on the SC-CO 2 method. Thermodynamic models were developed to study …

Quality by design for development, optimization and characterization of brucine ethosomal gel for skin cancer delivery

TA Ismail, TM Shehata, DI Mohamed, HS Elsewedy… - Molecules, 2021 - mdpi.com
Natural products have been extensively used for treating a wide variety of disorders. In
recent times, Brucine (BRU) as one of the natural medications extracted from seeds of nux …

Preparation, optimization and evaluation of chitosan-based avanafil nanocomplex utilizing antioxidants for enhanced neuroprotective effect on PC12 cells

M Kurakula, R Naveen N, B Patel, R Manne, DB Patel - Gels, 2021 - mdpi.com
(1) Introduction: in recent decades, interdisciplinary research on the utilization of natural
products as “active moiety carriers” was focused on due to their superior safety profile …

[HTML][HTML] Study of sonication parameters on PLA nanoparticles preparation by simple emulsion-evaporation solvent technique

E Ruiz, VH Orozco, LM Hoyos, LF Giraldo - European Polymer Journal, 2022 - Elsevier
The design of polymeric nanoparticles (PNPs) for delivery and controlled release of drugs
has been increasing in the last decades, where polymeric materials such as biocompatible …

Date Palm Extract (Phoenix dactylifera) PEGylated Nanoemulsion: Development, Optimization and Cytotoxicity Evaluation

HE Khalil, NK Alqahtani, HM Darrag, HIM Ibrahim… - Plants, 2021 - mdpi.com
Date palm fruit (Phoenix dactylifera) is reputed to have numerous biological activities,
including anticancer properties. To utilize the great fortune of this fruit, the current study …