[HTML][HTML] The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

[HTML][HTML] Role of gut microbiota and their metabolites on atherosclerosis, hypertension and human blood platelet function: a review

AK Duttaroy - Nutrients, 2021 - mdpi.com
Emerging data have demonstrated a strong association between the gut microbiota and the
development of cardiovascular disease (CVD) risk factors such as atherosclerosis …

[HTML][HTML] Endothelial dysfunction in obesity-induced inflammation: molecular mechanisms and clinical implications

IK Kwaifa, H Bahari, YK Yong, SM Noor - Biomolecules, 2020 - mdpi.com
Obesity is characterized by the excessive deposition of fat that may interfere with the normal
metabolic process of the body. It is a chronic condition associated with various metabolic …

[HTML][HTML] Inflammation, not cholesterol, is a cause of chronic disease

A Tsoupras, R Lordan, I Zabetakis - Nutrients, 2018 - mdpi.com
Since the Seven Countries Study, dietary cholesterol and the levels of serum cholesterol in
relation to the development of chronic diseases have been somewhat demonised. However …

Macrophage subsets in atherosclerosis

G Chinetti-Gbaguidi, S Colin, B Staels - Nature Reviews Cardiology, 2015 - nature.com
Macrophage accumulation within the vascular wall is a hallmark of atherosclerosis. In
atherosclerotic lesions, macrophages respond to various environmental stimuli, such as …

High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis

H Meng, VM Tutino, J Xiang… - American Journal of …, 2014 - Am Soc Neuroradiology
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …

[HTML][HTML] The role of gut microbiota in atherosclerosis and hypertension

J Ma, H Li - Frontiers in pharmacology, 2018 - frontiersin.org
In recent years, accumulating evidence has indicated the importance of gut microbiota in
maintaining human health. Gut dysbiosis is associated with the pathogenesis of a number of …

[HTML][HTML] The gut microbial metabolite trimethylamine N-oxide and cardiovascular diseases

J Zhen, Z Zhou, M He, HX Han, EH Lv… - Frontiers in …, 2023 - frontiersin.org
Morbidity and mortality of cardiovascular diseases (CVDs) are exceedingly high worldwide.
Researchers have found that the occurrence and development of CVDs are closely related …

Bioanalytical chemistry of cytokines–a review

JA Stenken, AJ Poschenrieder - Analytica chimica acta, 2015 - Elsevier
Cytokines are bioactive proteins produced by many different cells of the immune system.
Due to their role in different inflammatory disease states and maintaining homeostasis, there …

Functional roles of p38 mitogen‐activated protein kinase in macrophage‐mediated inflammatory responses

Y Yang, SC Kim, T Yu, YS Yi, MH Rhee… - Mediators of …, 2014 - Wiley Online Library
Inflammation is a natural host defensive process that is largely regulated by macrophages
during the innate immune response. Mitogen‐activated protein kinases (MAPKs) are proline …