The interaction between microglia and astrocytes significantly influences neuroinflammation.
Microglia/astrocytes, part of the neurovascular unit (NVU), are activated by various brain …

Intracerebral hemorrhage (ICH) accounts for 10–15% of all strokes and is associated with
high mortality and morbidity. Currently, no effective medical treatment is available to improve …

Approaches for the effective management of acute stroke are sparse, and many measures
for brain protection fail. However, our ability to modulate the immune system and modify the …

Intracerebral hemorrhage (ICH) is an often fatal type of stroke that kills≈ 30 000 people
annually in the United States. If the patient survives the ictus, then the resulting hematoma …

Intracerebral haemorrhage is an important public health problem leading to high rates of
death and disability in adults. Although the number of hospital admissions for intracerebral …

Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which
no specific treatment has been established yet. Although preclinical models of ICH have …

Intracerebral hemorrhage (ICH) is one of the most lethal stroke subtypes. Despite the high
morbidity and mortality associated with ICH, its pathophysiology has not been investigated …

Intracerebral hemorrhage (ICH) is a devastating clinical event without effective therapies.
Increasing evidence suggests that inflammatory mechanisms are involved in the …

Objective The NLRP3 (NALP3, cryopyrin) inflammasome, a key component of the innate
immune system, facilitates caspase‐1 and interleukin (IL)− 1β processing, which amplifies …

Neural stem cell (NSC) transplantation has been investigated as a means to reconstitute the
damaged brain after stroke. In this study, however, we investigated the effect on acute …