The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Aquaporin-5 (AQP5), belonging to the aquaporins (AQPs) family of transmembrane water
channels, facilitates osmotically driven water flux across biological membranes and the …

Mesenchymal stromal cells (MSCs) are attractive candidates for treating hepatic disorders
given their potential to enhance liver regeneration and function. The paracrine paradigm …

Cataract and presbyopia are the leading cause of vision loss and impaired vision,
respectively, worldwide. Changes in lens biochemistry and physiology with age are …

Purpose To investigate the role and mechanism of melatonin-loaded polymer polyvinyl
caprolactam–polyvinyl acetate–polyethyleneglycol graft copolymer micelles (Mel-Mic) in dry …

Aquaporins (AQPs) are a highly conserved group of membrane proteins that play critical
roles in water and small solute transport across epithelial and endothelial barriers. The aim …

Purpose AQP5−/− mice spontaneously exhibit dry eye symptoms. The purpose of this study
was to assess the endoplasmic reticulum (ER) stress-mediated inflammation generated by a …

Purpose: To spatially map aquaporin-5 (AQP5) expression in the bovine lens, molecularly
characterize cytoplasmic AQP5-containing vesicles in the outer cortex, and elucidate AQP5 …

The lens is transparent, non‐vascular, elastic and wrapped in a transparent capsule. The
lens oppacity of AQP5−/− mice was increased more than that of wild‐type (AQP5+/+) mice …

Purpose: The purpose of this study was to identify a new candidate gene for keratoconus
and congenital cataracts and further investigate its underlying pathogenic mechanisms …