Nucleic acid vaccines

G Ciaramella, A Bouchon, EYC Huang - US Patent 10,709,779, 2020 - Google Patents
US10709779B2 - Nucleic acid vaccines - Google Patents US10709779B2 - Nucleic acid
vaccines - Google Patents Nucleic acid vaccines Download PDF Info Publication number …

Polynucleotides encoding low density lipoprotein receptor

JL Ellsworth, JB Bolen, FM Gregoire… - US Patent 10,323,076, 2019 - Google Patents
HVYWMOMLDIMFJA-DPAQBDIFSA-N (3β)-Cholest-5-en-3-ol Chemical compound C1C=
C2C [C@@ H](O) CC [C@] 2 (C)[C@@ H] 2 [C@@ H] 1 [C@@ H] 1CC [C@ H]([C@ H](C) …

Modified polynucleotides encoding SIAH E3 ubiquitin protein ligase 1

T Chakraborty, A De Fougerolles - US Patent 9,255,129, 2016 - Google Patents
2014-03-03 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Combination piv3/hmpv rna vaccines

G Ciaramella, S Himansu - US Patent 10,272,150, 2019 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
58558175&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

[图书][B] Silencing of transgene expression: a gene therapy perspective

O Tolmachov, T Subkhankulova, T Tolmacheva - 2013 - repository.cam.ac.uk
The treatment of a number of diseases can be achieved through gene addition therapy,
where curative transgenes are established within the patient's cells after delivery with viral or …

Synthetic nucleic acids delivered by exosomes: a potential therapeutic for generelated metabolic brain diseases

R Liu, J Liu, X Ji, Y Liu - Metabolic brain disease, 2013 - Springer
Many brain diseases, including Alzheimer's disease, are associated with genetic
abnormalities. The search for more effective therapeutic approaches involving nucleic acids …

[HTML][HTML] Transfection of pseudouridine-modified mRNA encoding CPD-photolyase leads to repair of DNA damage in human keratinocytes: A new approach with future …

G Boros, E Miko, H Muramatsu, D Weissman… - … of Photochemistry and …, 2013 - Elsevier
UVB irradiation induces harmful photochemical reactions, including formation of
Cyclobutane Pyrimidine Dimers (CPDs) in DNA. Accumulation of unrepaired CPD lesions …

[HTML][HTML] Modified mRNA as a new therapeutic option for pediatric respiratory diseases and hemoglobinopathies

JS Antony, A Dewerth, A Haque… - Molecular and Cellular …, 2015 - Springer
Background The immunogenicity and limited stability of conventional messenger RNA
(mRNA) has traditionally restricted its potential therapeutic use. In 1992, the first clinical …

Trinucleotide mRNA cap analogs

G Butora, M Stanton, EJ Miracco - US Patent 11,866,754, 2024 - Google Patents
US11866754B2 - Trinucleotide mRNA cap analogs - Google Patents US11866754B2 -
Trinucleotide mRNA cap analogs - Google Patents Trinucleotide mRNA cap analogs Info …

[HTML][HTML] Fibroblast growth requires CT10 regulator of kinase (Crk) and Crk-like (CrkL)

T Park, M Koptyra, T Curran - Journal of Biological Chemistry, 2016 - ASBMB
CT10 regulator of kinase (Crk) and Crk-like (CrkL) are the cellular counterparts of the viral
oncogene v-Crk. Elevated levels of Crk and CrkL have been observed in many human …