Targeting angiogenesis in oncology, ophthalmology and beyond
Angiogenesis is an essential process in normal development and in adult physiology, but
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …
[HTML][HTML] Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors
Background Retinal vein occlusion (RVO) is the second most common retinal vascular
disorder that affected 16.4 million people worldwide in 2008. The last decade has seen new …
disorder that affected 16.4 million people worldwide in 2008. The last decade has seen new …
[HTML][HTML] IL-1 family members mediate cell death, inflammation and angiogenesis in retinal degenerative diseases
Inflammation underpins and contributes to the pathogenesis of many retinal degenerative
diseases. The recruitment and activation of both resident microglia and recruited …
diseases. The recruitment and activation of both resident microglia and recruited …
Retinal vascular events after mRNA and adenoviral-vectored COVID-19 vaccines—A case series
C Girbardt, C Busch, M Al-Sheikh, JM Gunzinger… - Vaccines, 2021 - mdpi.com
Background: To describe cases of retinal vascular events shortly after administration of
mRNA or adenoviral-vectored COVID-19 vaccines. Design: Retrospective, multicenter case …
mRNA or adenoviral-vectored COVID-19 vaccines. Design: Retrospective, multicenter case …
Optical coherence tomography-based consensus definition for lamellar macular hole
Background A consensus on an optical coherence tomography definition of lamellar
macular hole (LMH) and similar conditions is needed. Methods The panel reviewed relevant …
macular hole (LMH) and similar conditions is needed. Methods The panel reviewed relevant …
[HTML][HTML] Microneedle-enabled therapeutics delivery and biosensing in clinical trials
J Zhang, H Li, L Albakr, Y Zhang, A Lu, W Chen… - Journal of Controlled …, 2023 - Elsevier
Microneedles (MNs) are micron-sized protrusions attached to a range of devices that are
used in therapeutic delivery and diagnosis. Because MNs can be self-applied, are painless …
used in therapeutic delivery and diagnosis. Because MNs can be self-applied, are painless …
The 10-year incidence and risk factors of retinal vein occlusion: the Beijing eye study
JQ Zhou, L Xu, S Wang, YX Wang, QS You, Y Tu… - Ophthalmology, 2013 - Elsevier
OBJECTIVE: To assess the 10-year incidence of retinal vein occlusions (RVOs) and
associated factors in adult Chinese subjects. DESIGN: Population-based, longitudinal study …
associated factors in adult Chinese subjects. DESIGN: Population-based, longitudinal study …
Inherited risk factors for venous thromboembolism
I Martinelli, V De Stefano, PM Mannucci - Nature Reviews Cardiology, 2014 - nature.com
Venous thromboembolism (VTE) has important heritable components. In the past 20 years,
knowledge in this field has greatly increased with the identification of a number of gene …
knowledge in this field has greatly increased with the identification of a number of gene …
Anti‐VEGF therapy and the retina: an update
V Tah, HO Orlans, J Hyer, E Casswell… - Journal of …, 2015 - Wiley Online Library
Ocular angiogenesis and macular oedema are major causes of sight loss across the world.
Aberrant neovascularisation, which may arise secondary to numerous disease processes …
Aberrant neovascularisation, which may arise secondary to numerous disease processes …
[HTML][HTML] Prevalence and risk factors of retinal vein occlusion: the Gutenberg Health Study
KA Ponto, H Elbaz, T Peto, D Laubert‐Reh… - Journal of Thrombosis …, 2015 - Elsevier
Objective To determine the age‐and sex‐specific prevalence and determinants of retinal
vein occlusions (RVOs) in a large population‐based German cohort. Methods The …
vein occlusions (RVOs) in a large population‐based German cohort. Methods The …