Targeting angiogenesis in oncology, ophthalmology and beyond

Y Cao, R Langer, N Ferrara - Nature Reviews Drug Discovery, 2023 - nature.com
Angiogenesis is an essential process in normal development and in adult physiology, but
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …

[HTML][HTML] Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors

P Song, Y Xu, M Zha, Y Zhang, I Rudan - Journal of global health, 2019 - ncbi.nlm.nih.gov
Background Retinal vein occlusion (RVO) is the second most common retinal vascular
disorder that affected 16.4 million people worldwide in 2008. The last decade has seen new …

[HTML][HTML] IL-1 family members mediate cell death, inflammation and angiogenesis in retinal degenerative diseases

Y Wooff, SM Man, R Aggio-Bruce, R Natoli… - Frontiers in …, 2019 - frontiersin.org
Inflammation underpins and contributes to the pathogenesis of many retinal degenerative
diseases. The recruitment and activation of both resident microglia and recruited …

Retinal vascular events after mRNA and adenoviral-vectored COVID-19 vaccines—A case series

C Girbardt, C Busch, M Al-Sheikh, JM Gunzinger… - Vaccines, 2021 - mdpi.com
Background: To describe cases of retinal vascular events shortly after administration of
mRNA or adenoviral-vectored COVID-19 vaccines. Design: Retrospective, multicenter case …

Optical coherence tomography-based consensus definition for lamellar macular hole

JP Hubschman, A Govetto, RF Spaide… - British Journal of …, 2020 - bjo.bmj.com
Background A consensus on an optical coherence tomography definition of lamellar
macular hole (LMH) and similar conditions is needed. Methods The panel reviewed relevant …

[HTML][HTML] Microneedle-enabled therapeutics delivery and biosensing in clinical trials

J Zhang, H Li, L Albakr, Y Zhang, A Lu, W Chen… - Journal of Controlled …, 2023 - Elsevier
Microneedles (MNs) are micron-sized protrusions attached to a range of devices that are
used in therapeutic delivery and diagnosis. Because MNs can be self-applied, are painless …

The 10-year incidence and risk factors of retinal vein occlusion: the Beijing eye study

JQ Zhou, L Xu, S Wang, YX Wang, QS You, Y Tu… - Ophthalmology, 2013 - Elsevier
OBJECTIVE: To assess the 10-year incidence of retinal vein occlusions (RVOs) and
associated factors in adult Chinese subjects. DESIGN: Population-based, longitudinal study …

Inherited risk factors for venous thromboembolism

I Martinelli, V De Stefano, PM Mannucci - Nature Reviews Cardiology, 2014 - nature.com
Venous thromboembolism (VTE) has important heritable components. In the past 20 years,
knowledge in this field has greatly increased with the identification of a number of gene …

Anti‐VEGF therapy and the retina: an update

V Tah, HO Orlans, J Hyer, E Casswell… - Journal of …, 2015 - Wiley Online Library
Ocular angiogenesis and macular oedema are major causes of sight loss across the world.
Aberrant neovascularisation, which may arise secondary to numerous disease processes …

[HTML][HTML] Prevalence and risk factors of retinal vein occlusion: the Gutenberg Health Study

KA Ponto, H Elbaz, T Peto, D Laubert‐Reh… - Journal of Thrombosis …, 2015 - Elsevier
Objective To determine the age‐and sex‐specific prevalence and determinants of retinal
vein occlusions (RVOs) in a large population‐based German cohort. Methods The …