Description Proton pump inhibitors (PPIs) are among the most commonly used medications
in the world. Developed for the treatment and prevention of acid-mediated upper …

Background Polypharmacy and use of inappropriate medications have been linked to
increased risk of falls, hospitalizations, cognitive impairment, and death. The primary …

Polypharmacy is common in older adults and associated with inappropriate medication use,
adverse drug events, medication nonadherence, higher costs, and increased mortality …

Background Deprescribing, defined as discontinuing or reducing the dose of medications
that are no longer needed or for which the risks outweigh the benefits is a way to reduce …

Inappropriate polypharmacy is highly prevalent among older adults and presents a
significant healthcare concern. Conducting medication reviews and implementing …

Background Policies, protocols and processes within organisations can facilitate or hinder
guideline adoption. There is limited knowledge on the strategies used by organisations to …

Pain regimens, particularly for chronic cancer and noncancer pain, must balance the
important analgesic benefits against potential risks. Many effective and frequently used pain …

Abstract Background The revised Patients' Attitudes Towards Deprescribing (rPATD)
questionnaire explores older adults' views on deprescribing in general. Those views may …

Pharmacists play a key role in deprescribing medications. Incorporation of this concept into
pharmacy school curricula is important in ensuring that graduates can address the complex …

Polypharmacy poses a significant public health problem that disproportionately affects older
adults (≥ 65 years) since this population represents the largest consumers of medications …