Stem cell therapy and tissue engineering for correction of congenital heart disease

E Avolio, M Caputo, P Madeddu - Frontiers in cell and developmental …, 2015 - frontiersin.org
This review article reports on the new field of stem cell therapy and tissue engineering and
its potential on the management of congenital heart disease. To date, stem cell therapy has …

Pathophysiological impact of serum fibroblast growth factor 23 in patients with nonischemic cardiac disease and early chronic kidney disease

M Imazu, H Takahama, H Asanuma… - American Journal …, 2014 - journals.physiology.org
Although the important role of fibroblast growth factor (FGF) 23 on cardiac remodeling has
been suggested in advanced chronic kidney disease (CKD), little is known about serum (s) …

Comparison of rapidly proliferating, multipotent aortic valve‐derived stromal cells and valve interstitial cells in the human aortic valve

Y Huang, K Xu, T Zhou, P Zhu, N Dong… - Stem cells …, 2019 - Wiley Online Library
Aortic valve calcification is a common clinical disease, caused by valve interstitial cells
(VICs), which initiate the thickening and then calcification of valve leaflets. Classical valve …

Compositional change of gut microbiome and osteocalcin expressing endothelial progenitor cells in patients with coronary artery disease

T Toya, I Ozcan, MT Corban, JD Sara, EV Marietta… - PLoS …, 2021 - journals.plos.org
Osteogenic endothelial progenitor cells (EPCs) contribute to impaired endothelial repair and
promote coronary artery disease (CAD) and vascular calcification. Immature EPCs …

Coronary microvascular endothelial dysfunction is an independent predictor of development of osteoporosis in postmenopausal women

M Prasad, M Reriani, S Khosla, M Gössl… - Vascular health and …, 2014 - Taylor & Francis
Background A growing body of evidence links coronary artery atherosclerosis and
calcification to osteoporosis in women. The endothelium plays a critical role in maintaining …

Therapeutic strategy for atherosclerosis based on bone-vascular axis hypothesis

JM Kim, WS Lee, J Kim - Pharmacology & therapeutics, 2020 - Elsevier
As the world's older population grows, the disease burden of atherosclerosis is rapidly
increasing, causing significant morbidity and mortality worldwide. Despite recent …

In situ vascular tissue remodeling using biodegradable tubular scaffolds with incorporated growth factors and chemoattractant molecules

LV Antonova, VV Sevostyanova… - Комплексные …, 2018 - cyberleninka.ru
Background. Currently, the search for the bioactive molecules capable of promoting
formation of the vascular tissue is still ongoing. We have previously demonstrated that …

Reconstruction of the pulmonary artery by a novel biodegradable conduit engineered with perinatal stem cell-derived vascular smooth muscle cells enables …

MT Ghorbel, H Jia, MM Swim, D Iacobazzi, A Albertario… - Biomaterials, 2019 - Elsevier
Lack of growth potential of available grafts represents a bottleneck in the correction of
congenital heart defects. Here we used a swine small intestinal submucosa (SIS) graft …

Differences in calcification and osteogenic potential of herniated discs according to the severity of degeneration based on Pfirrmann grade: a cross-sectional study

J Shao, M Yu, L Jiang, F Wei, F Wu, Z Liu… - BMC Musculoskeletal …, 2016 - Springer
Background Herniated discs may exhibit calcification, and calcified discs may complicate
surgical treatment. However, the osteogenic potential and expression of osteogenic markers …

Association between circulating osteogenic progenitor cells and disability and frailty in older persons: the Nepean osteoporosis and frailty study

P Gunawardene, S Bermeo, C Vidal… - … Series A: Biomedical …, 2016 - academic.oup.com
Circulating osteogenic progenitor (COP) cells are considered as surrogates of the
mesenchymal repository in the body. In this study, we hypothesized that COP cells decrease …