Introduction Bicuspid aortic valve (BAV) is the most common congenital valvular heart defect
resulting from abnormal aortic cusp formation during heart development, where two of the …

Heart valves are sophisticated cellularised structures that perform a complex series of
dynamic functions during each cardiac cycle. The endothelial cells (ECs) that cover both …

For postmenopausal cardiovascular disease, long‐term estrogen therapy may increase the
risk of breast cancer. To reduce this risk, estrogen may be replaced with the phytoestrogen …

CAVD (calcific aortic valve disease) is the defining feature of AS (aortic stenosis). The
present study aimed to determine whether expression of ossification-related miRNAs is …

Although various osteogenic inducers contribute to the calcification of human aortic valve
interstitial cells, the cellular origin of calcification remains unclear. We …

The bone mineral density (BMD) loss is closely related to coronary heart disease (CAD). The
BMD measured at different locations differ in BMD values, the risk to CAD, and the capability …

A. National Heart, Lung, and Blood Institute: review and agenda for research (1). B. Left
ventricular mid-wall fibrosis is significantly related to mortality in patients with aortic stenosis …

Cardiovascular calcification is an independent risk factor and an established predictor of
adverse cardiovascular events. Despite concomitant factors leading to atherosclerosis and …

Aortic valve stenosis is the most common cardiac valve disease, and with current trends in
the population demographics, its prevalence is likely to rise, thus posing a major health and …

Diabetes reduces the number and induces dysfunction in circulating endothelial progenitor
cells (EPCs) by mechanisms that are still uncovered. This study aims to evaluate the …