Obstructive sleep apnea

LV Pham, J Jun, VY Polotsky - Handbook of Clinical Neurology, 2022 - Elsevier
Obstructive sleep apnea (OSA) is a disease that results from loss of upper airway muscle
tone leading to upper airway collapse during sleep in anatomically susceptible persons …

Impact of a weight-loss rehabilitation program on sleep apnea risk and subjective sleepiness in patients with overweight/obesity: The Dietsleep study

S Bailly, O Fabre, M Cals-Maurette, L Pantagis… - Journal of Clinical …, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is one of the most frequent chronic diseases, and comorbid
obesity occurs in more than 60% of cases. Variations in body weight influence both OSA …

CPAP resumption after a first termination and impact on all-cause mortality in France

JL Pépin, R Tamisier, AV Benjafield… - European …, 2024 - Eur Respiratory Soc
Background Continuation of continuous positive airway pressure (CPAP) therapy after initial
prescription has been shown to reduce all-cause mortality versus therapy termination …

[HTML][HTML] Assessment of the effect of the dual orexin receptor antagonist daridorexant on various indices of disease severity in patients with mild to moderate obstructive …

ML Boof, M Ufer, I Fietze, JL Pepin, AS Guern… - Sleep Medicine, 2022 - Elsevier
Background The dual orexin receptor antagonist daridorexant did not impact nighttime
respiratory function as assessed by the apnea/hypopnea index (AHI) and nocturnal oxygen …

Symptomatic response to CPAP in obstructive sleep apnea versus COPD-obstructive sleep apnea overlap syndrome: Insights from a large national registry

D Adler, S Bailly, PM Soccal, JP Janssens, M Sapène… - PLoS …, 2021 - journals.plos.org
Background The symptomatic response to continuous positive airway pressure (CPAP)
therapy in COPD-obstructive sleep apnea overlap syndrome (OVS) compared to OSA …

Telemedicine strategy to rescue CPAP therapy in sleep apnea patients with low treatment adherence: a pilot study

O Garmendia, R Farré, C Ruiz, M Suarez-Girón… - Journal of clinical …, 2021 - mdpi.com
Patients with sleep apnea are usually treated with continuous positive airway pressure
(CPAP). This therapy is very effective if the patient′ s adherence is satisfactory. However …

Adaptive responses to chronic intermittent hypoxia: contributions from the European Sleep Apnoea Database (ESADA) Cohort

MR Bonsignore… - The Journal of …, 2023 - Wiley Online Library
Obstructive sleep apnoea (OSA) is a common disease in the general population, and is
associated with increased cardiovascular risk and several comorbidities. Obesity favours …

Relationship between self-reported sleepiness and positive airway pressure treatment adherence in obstructive sleep apnea

PA Cistulli, JP Armitstead, A Malhotra… - Annals of the …, 2023 - atsjournals.org
Rationale: Positive airway pressure (PAP) is the first-choice treatment for obstructive sleep
apnea (OSA). However, its real-world effectiveness is often questioned because of usage …

Endotyping, phenotyping and personalised therapy in obstructive sleep apnoea: are we there yet?

CD Turnbull, JR Stradling - thorax, 2023 - thorax.bmj.com
Obstructive sleep apnoea (OSA) was traditionally thought to be mainly caused by obesity
and upper airway crowding, and hence OSA management was not personalised according …

L-Citrulline supplementation reduces blood pressure and myocardial infarct size under chronic intermittent hypoxia, a major feature of sleep apnea syndrome

B Ozcan, B Blachot-Minassian, S Paradis, L Mazière… - Antioxidants, 2022 - mdpi.com
Intermittent hypoxia (IH) is a landmark of obstructive sleep apnea (OSA) at the core of the
cardiovascular consequences of OSA. IH triggers oxidative stress, a major underlying …