Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium

L Schomburg, U Schweizer - Biochimica et Biophysica Acta (BBA)-General …, 2009 - Elsevier
The expression of selenoproteins is controlled on each one of the textbook steps of protein
biosynthesis, ie, during gene transcription, RNA processing, translation and …

Micronutrient deficiencies in heart failure: Mitochondrial dysfunction as a common pathophysiological mechanism?

N Bomer, MG Pavez‐Giani… - Journal of Internal …, 2022 - Wiley Online Library
Heart failure is a devastating clinical syndrome, but current therapies are unable to abolish
the disease burden. New strategies to treat or prevent heart failure are urgently needed …

Selenium and the thyroid: a close-knit connection

LH Duntas - The Journal of Clinical Endocrinology & …, 2010 - academic.oup.com
Context: The recent recognition that the essential trace element selenium is incorporated as
selenocysteine in all three deiodinases has decisively confirmed the clear-cut link between …

Selenium, selenoproteins and cancer of the thyroid

RM Rua, F Nogales, O Carreras, ML Ojeda - Journal of Trace Elements in …, 2023 - Elsevier
Selenium is an essential mineral element with important biological functions for the whole
body through incorporation into selenoproteins. This element is highly concentrated in the …

[HTML][HTML] Selenoproteins in the human placenta: how essential is selenium to a healthy start to life?

C Hogan, AV Perkins - Nutrients, 2022 - mdpi.com
Selenium is an essential trace element required for human health, and selenium deficiency
has been associated with many diseases. The daily recommended intake of selenium is 60 …

[HTML][HTML] IGF-1, the cross road of the nutritional, inflammatory and hormonal pathways to frailty

M Maggio, F De Vita, F Lauretani, V Buttò, G Bondi… - Nutrients, 2013 - mdpi.com
The decline in functional capacity is a heterogeneous phenomenon in the elderly. An
accelerated ageing determines a frail status. It results in an increased vulnerability to …

Selenium status, thyroid volume, and multiple nodule formation in an area with mild iodine deficiency

LB Rasmussen, L Schomburg, J Köhrle… - European Journal of …, 2011 - academic.oup.com
Objective The objective was to study the associations between serum selenium
concentration and thyroid volume, as well as the association between serum selenium …

[HTML][HTML] Biofortification of cereals with foliar selenium and iodine could reduce hypothyroidism

G Lyons - Frontiers in Plant Science, 2018 - frontiersin.org
Concurrent selenium and iodine deficiencies are widespread, in both developing and
developed countries. Salt iodisation is insufficient to ensure global iodine adequacy, with an …

Detection of selenocysteine with a ratiometric near-infrared fluorescent probe in cells and in mice thyroid diseases model

X Luo, R Wang, C Lv, G Chen, J You, F Yu - Analytical chemistry, 2019 - ACS Publications
The pathological progression of thyroid diseases poses a serious threat to human health.
Because thyroid diseases are closely related to selenocysteine (Sec), it is necessary to …

Selenium in cereals: Insight into species of the element from total amount

M Xie, X Sun, P Li, X Shen… - Comprehensive Reviews in …, 2021 - Wiley Online Library
Selenium (Se) is a trace mineral micronutrient essential for human health. The diet is the
main source of Se intake. Se‐deficiency is associated with many diseases, and up to 1 …