Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin …

CA Bousman, JM Stevenson… - Clinical …, 2023 - Wiley Online Library
Serotonin reuptake inhibitor antidepressants, including selective serotonin reuptake
inhibitors (SSRIs; ie, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and …

[HTML][HTML] Oxidative stress in depression: the link with the stress response, neuroinflammation, serotonin, neurogenesis and synaptic plasticity

AS Correia, A Cardoso, N Vale - Antioxidants, 2023 - mdpi.com
Depression is a prevalent, complex, and highly debilitating disease. The full comprehension
of this disease is still a global challenge. Indeed, relapse, recurrency, and therapeutic …

The role of exercise in the treatment of depression: biological underpinnings and clinical outcomes

RE Ross, CJ VanDerwerker, ME Saladin… - Molecular …, 2023 - nature.com
Globally, depression is a leading cause of disability and has remained so for decades.
Antidepressant medications have suboptimal outcomes and are too frequently associated …

New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications

OA Andreassen, GFL Hindley, O Frei… - World …, 2023 - Wiley Online Library
Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

[HTML][HTML] A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression

S Jauhar, D Arnone, DS Baldwin, M Bloomfield… - Molecular …, 2023 - nature.com
A recent “umbrella” review examined various biomarkers relating to the serotonin system,
and concluded there was no consistent evidence implicating serotonin in the …

Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications

M Nimgampalle, H Chakravarthy, S Sharma… - Ageing Research …, 2023 - Elsevier
Neurotransmitters serve as chemical messengers playing a crucial role in information
processing throughout the nervous system, and are essential for healthy physiological and …

Health psychology: Theory, research and practice

DF Marks, M Murray, A Locke, RA Annunziato… - 2024 - torrossa.com
Welcome to Health Psychology: Theory, Research and Practice (Seventh Edition). This
textbook provides an in-depth introduction to the growing field of health psychology. It is …

Fifty years on: Serotonin and depression

S Jauhar, PJ Cowen… - Journal of …, 2023 - journals.sagepub.com
It has been over 50 years since the original serotonin hypothesis was proposed by the
British Psychiatrist Alec Coppen. Recently, some authors have questioned the validity of the …

Burning down the house: reinventing drug discovery in psychiatry for the development of targeted therapies

AH Miller, CL Raison - Molecular Psychiatry, 2023 - nature.com
Despite advances in neuroscience, limited progress has been made in developing new and
better medications for psychiatric disorders. Available treatments in psychiatry rely on a few …

[HTML][HTML] Screening for neuroprotective and rapid antidepressant-like effects of 20 essential oils

KN Tran, NPK Nguyen, LTH Nguyen, HM Shin, IJ Yang - Biomedicines, 2023 - mdpi.com
Depression is a serious psychiatric disorder with high prevalence, and the delayed onset of
antidepressant effects remains a limitation in the treatment of depression. This study aimed …