Ovarian cancer is the leading cause of gynecological cancer-related death. Drug resistance
is the bottleneck in ovarian cancer treatment. The increasing use of novel drugs in clinical …

Ground‐breaking research in disease biology and continuous efforts in method
development have uncovered a range of potential new drug targets. Increasingly, the drug …

Abstract Solute carrier family 25 (SLC25) encodes transport proteins at the inner
mitochondrial membrane and functions as carriers for metabolites. Although SLC25 genetic …

Introduction: The oncogenic transformation is driven by genetic and epigenetic alterations
influencing cancer cell fate. These alterations also result in metabolic reprogramming by …

Solute carrier (SLC) transporters play a dual role in the occurrence and progression of
tumours by acting as both suppressors and promoters. However, the overall impact of SLC …

Perturbation of solute carriers (SLCs) has been implicated in metabolic disorders and
cancer, highlighting the potential for drug discovery and therapeutic opportunities. However …

Recent findings have suggested that solute carrier (SLC) transporters play an important role
in tumor development and progression, and alterations in the expression of individual SLC …

Altered metabolism, such as aerobic glycolysis or the Warburg effect, has been recognized
as characteristics of tumor cells for almost a century. Since then, there is accumulating …

Indole diterpenes are a large class of secondary metabolites produced by fungi, possessing
a cyclic diterpenoid backbone and an indole moiety. Novel structures and important …

Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor, with an extremely
poor prognosis due to resistance to standard-of-care treatments. Strong evidence suggests …