In order to efficiently deliver anticancer agents to tumors, biocompatible nanoparticles or
bioconjugates, including antibody–drug conjugates (ADCs), have recently been designed …

While small hydrophilic therapeutic molecules have proved to be exceptionally effective in
curing diseases, their in vivo efficacy remains low. Small molecule therapeutics infused in …

Liposomes are self-assembled bilayer vesicles which have attracted a great deal of interest
as potential carriers for a wide range of therapeutic agents. They have significantly …

Ligand-targeted nanoparticles are emerging drug delivery vehicles for cancer therapy. Here,
we demonstrate that the cellular uptake of peptide-targeted liposomes and micelles can be …

Thermo-sensitive vesicles are a promising tool for triggering the release of drugs to solid
tumours when used in combination with mild hyperthermia. Responsivity to temperature …

The aggressiveness of melanoma and lack of effective therapies incite the discovery of
novel strategies. Recently, a new dual acting hybrid molecule (HM), combining a triazene …

More than 20 years after its approval by the Food and Drug Administration (FDA), liposomal
doxorubicin (DOX) is still the drug of choice for the treatment of breast cancer and other …

The success of subunit vaccines has been hampered by the problems of weak or short-term
immunity and the lack of availability of nontoxic, potent adjuvants. It would be desirable to …

The advent of nanoparticle DDSs (drug delivery systems, nano-DDSs) is opening new
pathways to understanding physiology and pathophysiology at the nanometer scale. A nano …

Extracellular vesicles (EVs) are membrane enclosed vesicles that are shed by almost all cell
types, and play a fundamental role in cell-to-cell communication. The discovery that EVs are …