Efficient estimation of personalized biventricular mechanical function employing gradient‐based optimization

H Finsberg, C Xi, JL Tan, L Zhong… - … journal for numerical …, 2018 - Wiley Online Library
Individually personalized computational models of heart mechanics can be used to estimate
important physiological and clinically‐relevant quantities that are difficult, if not impossible …

[HTML][HTML] A new active contraction model for the myocardium using a modified hill model

D Guan, H Gao, L Cai, X Luo - Computers in Biology and Medicine, 2022 - Elsevier
This study develops a new hybrid active contraction model for myocardial dynamics
abstracted from sarcomere by combining the phenomenologically active-stress based Hill …

Mixed Kirchhoff stress–displacement–pressure formulations for incompressible hyperelasticity

PE Farrell, LF Gatica, BP Lamichhane… - Computer Methods in …, 2021 - Elsevier
The numerical approximation of hyperelasticity must address nonlinear constitutive laws,
geometric nonlinearities associated with large strains and deformations, the imposition of …

A transmurally heterogeneous orthotropic activation model for ventricular contraction and its numerical validation

L Barbarotta, S Rossi, L Dedè… - International journal for …, 2018 - Wiley Online Library
Abstract Models for cardiac mechanics require an activation mechanism properly
representing the stress‐strain relations in the contracting myocardium. In this paper, we …

A computational study of right ventricular mechanics in a rat model of pulmonary arterial hypertension

OO Odeigah, ED Kwan, KM Garcia, H Finsberg… - Frontiers in …, 2024 - frontiersin.org
Pulmonary arterial hypertension (PAH) presents a significant challenge to right ventricular
(RV) function due to progressive pressure overload, necessitating adaptive remodeling in …

High‐resolution data assimilation of cardiac mechanics applied to a dyssynchronous ventricle

G Balaban, H Finsberg, HH Odland… - … journal for numerical …, 2017 - Wiley Online Library
Computational models of cardiac mechanics, personalized to a patient, offer access to
mechanical information above and beyond direct medical imaging. Additionally, such …

Adjoint multi-start-based estimation of cardiac hyperelastic material parameters using shear data

G Balaban, MS Alnæs, J Sundnes… - … and modeling in …, 2016 - Springer
Cardiac muscle tissue during relaxation is commonly modeled as a hyperelastic material
with strongly nonlinear and anisotropic stress response. Adapting the behavior of such a …

Calibration of a fully coupled electromechanical meshless computational model of the heart with experimental data

È Lluch, O Camara, R Doste, B Bijnens… - Computer Methods in …, 2020 - Elsevier
Most electromechanical cardiac models available in the literature are based on the Finite
Element Method (FEM). Despite FEM's high accuracy, its performance is intrinsically …

[PDF][PDF] Mechanical imaging of dynamic patient stress patterns

HN Finsberg, G Balaban, J Sundnes, HH Odland… - 2015 - web-backend.simula.no
INTRODUCTION Abnormal stresses are hypothesized to be a key driver in remodelling
processes associated with heart failure [7]. However, it is currently impossible to measure …

From pixels to particles: multi-physics meshless model of the heart

È Lluc Álvarez - 2019 - repositori.upf.edu
The functioning of the heart, which main role is pumping blood to the rest of the body, is the
result of a complex combination of multi-scale physical processes from the molecular to the …