[HTML][HTML] Estrogen receptor β modulates apoptosis complexes and the inflammasome to drive the pathogenesis of endometriosis

SJ Han, SY Jung, SP Wu, SM Hawkins, MJ Park, S Kyo… - Cell, 2015 - cell.com
Alterations in estrogen-mediated cellular signaling play an essential role in the
pathogenesis of endometriosis. In addition to higher estrogen receptor (ER) β levels …

[HTML][HTML] Pathogenesis of deep endometriosis

S Gordts, P Koninckx, I Brosens - Fertility and sterility, 2017 - Elsevier
The pathophysiology of (deep) endometriosis is still unclear. As originally suggested by
Cullen, change the definition “deeper than 5 mm” to “adenomyosis externa.” With the …

[HTML][HTML] Gut microbiota and microbiota-derived metabolites promotes endometriosis

SB Chadchan, SK Naik, P Popli, C Talwar… - Cell Death …, 2023 - nature.com
Endometriosis is a pathological condition of the female reproductive tract characterized by
the existence of endometrium-like tissue at ectopic sites, affecting 10% of women between …

[HTML][HTML] Endometriosis associated infertility: a critical review and analysis on etiopathogenesis and therapeutic approaches

L Filip, F Duică, A Prădatu, D Crețoiu, N Suciu… - Medicina, 2020 - mdpi.com
Endometriosis represents a frequently diagnosed gynecological affliction in the reproductive
timespan of women, defined by symptoms ranging from pelvic pain to infertility. A complex …

[HTML][HTML] Endometriosis: a disease with few direct treatment options

PRC França, ACP Lontra, PD Fernandes - Molecules, 2022 - mdpi.com
Endometriosis is a gynecological condition characterized by the growth of endometrium-like
tissues inside and outside the pelvic cavity. The evolution of the disease can lead to infertility …

[HTML][HTML] Associations between endometriosis and gut microbiota

A Svensson, L Brunkwall, B Roth… - Reproductive …, 2021 - Springer
The gut microbiota has been associated with many diseases, including endometriosis.
However, very few studies have been conducted on this topic in human. This study aimed to …

Endometriosis and the microbiome: a systematic review

M Leonardi, C Hicks, F El‐Assaad… - … Journal of Obstetrics …, 2020 - Wiley Online Library
Background The aetiology and pathogenesis of endometriosis are still under investigation.
There is evidence that there is a complex bidirectional interaction between endometriosis …

[HTML][HTML] Endometriosis: where are we and where are we going?

AD Greene, SA Lang, JA Kendziorski… - Reproduction …, 2016 - ncbi.nlm.nih.gov
Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

[HTML][HTML] Targeting macrophages as a potential therapeutic intervention: impact on inflammatory diseases and cancer

M Ponzoni, F Pastorino, D Di Paolo, P Perri… - International journal of …, 2018 - mdpi.com
Macrophages, cells belonging to the innate immune system, present a high plasticity grade,
being able to change their phenotype in response to environmental stimuli. They play …

Gut microbiota–derived short-chain fatty acids protect against the progression of endometriosis

SB Chadchan, P Popli, CR Ambati… - Life science …, 2021 - life-science-alliance.org
Worldwide,∼ 196 million are afflicted with endometriosis, a painful disease in which
endometrial tissue implants and proliferates on abdominal peritoneal surfaces. Theories on …