Dietary and physiological effects of zinc on the immune system

I Wessels, HJ Fischer, L Rink - Annual review of nutrition, 2021 - annualreviews.org
Evidence for the importance of zinc for all immune cells and for mounting an efficient and
balanced immune response to various environmental stressors has been accumulating in …

The role of zinc in the endocrine system

AK Baltaci, R Mogulkoc, SB Baltaci - 2019 - acikerisim.selcuk.edu.tr
Özet Zinc is essential in the regulation of a variety of physiological and biochemical events
in the organism. It plays a critical role in maintaining the cell membrane integrity, protein …

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

A Williamson, DM Norris, X Yin, KA Broadaway… - Nature …, 2023 - nature.com
Distinct tissue-specific mechanisms mediate insulin action in fasting and postprandial states.
Previous genetic studies have largely focused on insulin resistance in the fasting state …

Renin‐angiotensin system revisited

F Fyhrquist, O Saijonmaa - Journal of internal medicine, 2008 - Wiley Online Library
New components and functions of the renin‐angiotensin system (RAS) are still being
unravelled. The classical RAS as it looked in the middle 1970s consisted of circulating renin …

Zinc and diabetes—clinical links and molecular mechanisms

J Jansen, W Karges, L Rink - The Journal of nutritional biochemistry, 2009 - Elsevier
Zinc is an essential trace element crucial for the function of more than 300 enzymes and it is
important for cellular processes like cell division and apoptosis. Hence, the concentration of …

GLUT4 exocytosis

J Stöckli, DJ Fazakerley, DE James - Journal of cell science, 2011 - journals.biologists.com
GLUT4 is an insulin-regulated glucose transporter that is responsible for insulin-regulated
glucose uptake into fat and muscle cells. In the absence of insulin, GLUT4 is mainly found in …

An IFN-γ–induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I–presented peptides

T Saric, SC Chang, A Hattori, IA York, S Markant… - Nature …, 2002 - nature.com
Precursors to major histocompatibility complex (MHC) class I–presented peptides with extra
NH2-terminal residues can be efficiently trimmed to mature epitopes in the endoplasmic …

Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance.

WT Garvey, L Maianu, JH Zhu… - The Journal of …, 1998 - Am Soc Clin Investig
Insulin resistance is instrumental in the pathogenesis of type 2 diabetes mellitus and the
Insulin Resistance Syndrome. While insulin resistance involves decreased glucose transport …

Insulin signaling pathways in time and space

AR Saltiel, JE Pessin - Trends in cell biology, 2002 - cell.com
Despite remarkable progress in dissecting the signaling pathways that are crucial for the
metabolic effects of insulin, the molecular basis for the specificity of its cellular actions is not …

The brain renin–angiotensin system: location and physiological roles

MJ McKinley, AL Albiston, AM Allen, ML Mathai… - The international journal …, 2003 - Elsevier
Angiotensinogen, the precursor molecule for angiotensins I, II and III, and the enzymes
renin, angiotensin-converting enzyme (ACE), and aminopeptidases A and N may all be …