[HTML][HTML] The role of circulating tumor cells in the metastatic cascade: biology, technical challenges, and clinical relevance

H Dianat-Moghadam, M Azizi, Z Eslami-S… - Cancers, 2020 - mdpi.com
Metastases and cancer recurrence are the main causes of cancer death. Circulating Tumor
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …

Frequent FOS gene rearrangements in epithelioid hemangioma: a molecular study of 58 cases with morphologic reappraisal

SC Huang, L Zhang, YS Sung, CL Chen… - The American journal …, 2015 - journals.lww.com
Epithelioid hemangioma (EH) is a unique benign vasoformative tumor composed of
epithelioid endothelial cells. Although a small subset of EHs with atypical features harbor …

[HTML][HTML] Synthesis and characterization of copper nanoparticles stabilized with Quisqualis indica extract: evaluation of its cytotoxicity and apoptosis in B16F10 …

R Mukhopadhyay, J Kazi, MC Debnath - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Green synthesis of metallic nanoparticles is a cost-effective environment-friendly technique
and Quisqualis indica has ethnomedicinal values. With this background in this study, the …

The ubiquitin–proteasome system in breast cancer

D Han, L Wang, S Jiang, Q Yang - Trends in molecular medicine, 2023 - cell.com
Ubiquitin–proteasome system (UPS) is a selective proteolytic system that is associated with
the expression or function of target proteins and participates in various physiological and …

[HTML][HTML] Sarcoma-targeting peptide-decorated polypeptide nanogel intracellularly delivers shikonin for upregulated osteosarcoma necroptosis and diminished …

S Li, T Zhang, W Xu, J Ding, F Yin, J Xu, W Sun… - Theranostics, 2018 - ncbi.nlm.nih.gov
Purpose: Osteosarcoma is the most common primary bone cancer and is notorious for
pulmonary metastasis, representing a major threat to pediatric patients. An effective drug …

[HTML][HTML] Molecular pathways involved in the anti-cancer activity of flavonols: a focus on myricetin and kaempferol

MR Felice, A Maugeri, G De Sarro, M Navarra… - International Journal of …, 2022 - mdpi.com
Natural compounds have always represented valuable allies in the battle against several
illnesses, particularly cancer. In this field, flavonoids are known to modulate a wide panel of …

[HTML][HTML] Curcumin inhibits proliferation, migration, invasion and promotes apoptosis of retinoblastoma cell lines through modulation of miR-99a and JAK/STAT …

Y Li, W Sun, N Han, Y Zou, D Yin - BMC cancer, 2018 - Springer
Background Curcumin, a primary active ingredient extracted from the Curcuma longa, has
been recently identified as a potential anti-tumor agent in multiple kinds of cancers …

[HTML][HTML] F-actin interactome reveals vimentin as a key regulator of actin organization and cell mechanics in mitosis

MP Serres, M Samwer, BAT Quang, G Lavoie… - Developmental cell, 2020 - cell.com
Most metazoan cells entering mitosis undergo characteristic rounding, which is important for
accurate spindle positioning and chromosome separation. Rounding is driven by contractile …

[HTML][HTML] Establishment of a pancreatic adenocarcinoma molecular gradient (PAMG) that predicts the clinical outcome of pancreatic cancer

R Nicolle, Y Blum, P Duconseil, C Vanbrugghe… - …, 2020 - thelancet.com
Background A significant gap in pancreatic ductal adenocarcinoma (PDAC) patient's care is
the lack of molecular parameters characterizing tumours and allowing a personalized …

Increased expression of Slug and Vimentin as novel predictive biomarkers for lymph node metastasis and poor prognosis in colorectal cancer

Y Toiyama, H Yasuda, S Saigusa, K Tanaka… - …, 2013 - academic.oup.com
Slug and Vimentin genes play a critical role in regulating epithelial–mesenchymal transition
(EMT) via downregulation of epithelial markers and upregulation of mesenchymal markers …