The house dust mite (HDM) is a major perennial allergen source and a significant cause of
allergic rhinitis and allergic asthma. However, awareness of the condition remains generally …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome associated
with abnormal inflammatory immune responses of the lung to noxious particles and gases …

BETWEEN BEDSIDE AND BENCH differentiation of naive T lymphocytes toward TH2 cells,
which produce cytokines such as interleukin-4 (IL-4), IL-5, IL-9 and IL-13 (ref. 2). Allergic …

House dust mite (HDM) is one of the most common allergens worldwide. In this study, we
have addressed the involvement of IL-1 in the interaction between HDM and the innate …

Allergic sensitization to inhaled antigens is common but poorly understood. Although lung
epithelial cells were initially merely regarded as a passive barrier impeding allergen …

House dust mites (HDM; Dermatophagoides sp.) are one of the commonest aeroallergens
worldwide and up to 85% of asthmatics are typically HDM allergic. Allergenicity is …

Allergic inflammation is due to a complex interplay between several inflammatory cells,
including mast cells, basophils, lymphocytes, dendritic cells, eosinophils, and sometimes …

The adoption of the concept that asthma is primarily a disease most frequently associated
with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the widely held concept …

Since novel treatments to target eosinophilic inflammation in Type 2 asthma are emerging,
we aimed to evaluate and meta-analyze the efficacy of monoclonal antibodies to reduce …

Dendritic cells (DCs) are the primary antigen-presenting cells and play key roles in the
orchestration of the innate and adaptive immune system. Targeting DCs by nanotechnology …