[HTML][HTML] Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer's disease
Failed proteostasis is a well-documented feature of Alzheimer's disease, particularly,
reduced protein degradation and clearance. However, the contribution of failed proteostasis …
reduced protein degradation and clearance. However, the contribution of failed proteostasis …
[HTML][HTML] IL-34 exacerbates pathogenic features of Alzheimer's disease and calvaria osteolysis in triple transgenic (3x-Tg) female mice
Hallmark features of Alzheimer's disease (AD) include elevated accumulation of aggregated
Aβ40 and Aβ42 peptides, hyperphosphorylated Tau (p-Tau), and neuroinflammation …
Aβ40 and Aβ42 peptides, hyperphosphorylated Tau (p-Tau), and neuroinflammation …
Dexmedetomidine mitigates neuroinflammation in an Alzheimer's disease mouse model via the miR-204-3p/FBXL7 signaling axis
X Lian, X Zhang, W Chen, F Xue, G Wang - Brain Research, 2024 - Elsevier
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by
neuroinflammation. Dexmedetomidine (Dex) is known for its neuroprotective properties in …
neuroinflammation. Dexmedetomidine (Dex) is known for its neuroprotective properties in …
Resolving neuroinflammatory and social deficits in ASD model mice: Dexmedetomidine downregulates NF-κB/IL-6 pathway via α2AR
ZK Liang, W Xiong, C Wang, L Chen, X Zou… - Brain, Behavior, and …, 2024 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that severely affects
individuals' daily life and social development. Unfortunately, there are currently no effective …
individuals' daily life and social development. Unfortunately, there are currently no effective …
[HTML][HTML] Panaxcerol D from Panax ginseng ameliorates the memory impairment induced by cholinergic blockade or Aβ25–35 peptide in mice
K Park, R Kim, K Cho, CH Kong, M Jeon… - Journal of Ginseng …, 2024 - Elsevier
Background Alzheimer's disease (AD) has memory impairment associated with aggregation
of amyloid plaques and neurofibrillary tangles in the brain. Although anti-amyloid β (Aβ) …
of amyloid plaques and neurofibrillary tangles in the brain. Although anti-amyloid β (Aβ) …