At any point 1–5 days following ascent to altitudes≥ 2500 m, individuals are at risk of
developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome …

Hypoxic pulmonary vasoconstriction (HPV) represents a fundamental difference between
the pulmonary and systemic circulations. HPV is active in utero, reducing pulmonary blood …

The increase in heart rate is related to increased sympathetic activity and vagal withdrawal.
10 For a given level of exercise, heart rate is greater at altitude11 (Figure 2), although the …

The European Respiratory Society (ERS) Research Seminar entitled “Pulmonary vascular
endothelium: orchestra conductor in respiratory diseases-highlights from basic research to …

Alveolar hypoxia is the most prominent feature of high altitude environment with well-known
consequences for the cardio-pulmonary system, including development of pulmonary …

Abstract Swenson, Erik R. Hypoxic pulmonary vasoconstriction. High Alt Med Biol 14: 101–
110, 2013.—Hypoxic pulmonary vasoconstriction (HPV) continues to fascinate …

It is estimated that> 140 million people live above 2500 m in various regions of the world. 1
There are many challenges to living at high altitude, but chronic exposure to alveolar …

High-altitude pulmonary edema (HAPE) is an uncommon form of pulmonary edema that
occurs in healthy individuals within a few days of arrival at altitudes above 2,500–3,000 m …

Amid efforts to care for the large number of patients with coronavirus disease (COVID-19),
there has been considerable speculation about whether the lung injury seen in these …

High-altitude illnesses have profound consequences on the health of many unsuspecting
and otherwise healthy individuals who sojourn to high altitude for recreation and work. The …