The uncontrollable spread of superbugs calls for new approaches in dealing with microbial-
antibiotic resistance. Accordingly, the anti-virulence approach has arisen as an attractive …

Bacterial secondary metabolites represent an invaluable source of bioactive molecules for
the pharmaceutical and agrochemical industries. Although screening campaigns for the …

With the widespread use and abuse of antibiotics, Helicobacter pylori (H. pylori) has become
seriously drug resistant. The development of new antibiotics is an important way to solve H …

BACKGROUND Bacterial virulence factors are involved in various biological processes and
mediate persistent bacterial infections. Focusing on virulence factors of phytopathogenic …

Most bacteria exist and interact within polymicrobial communities. These interactions
produce unique compounds, increase virulence and augment antibiotic resistance. One …

Staphylococcus aureus uses quorum sensing and nutrient availability to control the
expression of agr-regulated virulence factors. Quorum sensing is mediated by autoinducing …

Staphylococcus aureus are gram-positive bacteria responsible for a wide array of diseases,
ranging from skin and soft tissue infections to more chronic illnesses such as toxic shock …

Pseudomonas aeruginosa, a nosocomial pathogen, has strong biofilm capabilities,
representing the main source of infection in the human body. Repurposing existing drugs …

In cystic fibrosis individuals, chronic lung infections and hospital-acquired pneumonia are
caused by Pseudomonas aeruginosa. P. aeruginosa generates siderophores such as …

Pseudomonas aeruginosa uses quorum sensing to regulate the expression of virulence
factors. In static environments, spatial structures, such as biofilms, can increase the …