Differential mortality in COVID-19 patients from India and western countries

VK Jain, K Iyengar, A Vaish, R Vaishya - Diabetes & Metabolic Syndrome …, 2020 - Elsevier
Background and aims COVID-19 disease has been associated with disproportionate
mortality amongst world population. We try to elucidate various reasons for lower mortality …

Of vascular defense, hemostasis, cancer, and platelet biology: an evolutionary perspective

DG Menter, V Afshar-Kharghan, JP Shen… - Cancer and Metastasis …, 2022 - Springer
We have established considerable expertise in studying the role of platelets in cancer
biology. From this expertise, we were keen to recognize the numerous venous-, arterial …

Structure of furin protease binding to SARS-CoV-2 spike glycoprotein and implications for potential targets and virulence

N Vankadari - The journal of physical chemistry letters, 2020 - ACS Publications
The COVID-19 pandemic is an urgent global health emergency, and the presence of Furin
site in the SARS-CoV-2 spike glycoprotein alters virulence and warrants further molecular …

Structure of the SARS-CoV-2 Nsp1/5′-untranslated region complex and implications for potential therapeutic targets, a vaccine, and virulence

N Vankadari, NN Jeyasankar… - The journal of physical …, 2020 - ACS Publications
SARS-CoV-2 is the cause of the ongoing Coronavirus disease 19 (COVID-19) pandemic
around the world causing pneumonia and lower respiratory tract infections. In understanding …

Emerging RNA-dependent RNA polymerase mutation in a remdesivir-treated B-cell immunodeficient patient with protracted coronavirus disease 2019

M Martinot, A Jary, S Fafi-Kremer… - Clinical Infectious …, 2021 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered virus
for which remdesivir is the only antiviral available. We report the occurrence of a mutation in …

[PDF][PDF] Remdesivir failure with SARS-CoV-2 RNA-dependent RNA-polymerase mutation in a B-cell immunodeficient patient with protracted Covid-19

M Martinot, A Jary, S Fafi-Kremer, V Leducq… - Clin Infect …, 2020 - scholar.archive.org
SARS-CoV-2 is a new pandemic virus for which Remdesivir is the only antiviral available.
We report the occurrence of a mutation in the RdRP (D484Y) following failure of remdesivir …

Structure of human TMPRSS2 in complex with SARS-CoV-2 spike glycoprotein and implications for potential therapeutics

N Vankadari, V Ketavarapu, S Mitnala… - The Journal of …, 2022 - ACS Publications
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has infected more than 520 million people around …

Association of polymorphisms in tumor necrosis factors with SARS‐CoV‐2 infection and mortality rate: A case‐control study and in silico analyses

M Heidari Nia, M Rokni, S Mirinejad… - Journal of Medical …, 2022 - Wiley Online Library
The present coronavirus disease 2019 (COVID‐19) is spreading rapidly and existing data
has suggested a number of susceptibility factors for developing a severe course of the …

Dietary polyphenols mitigate SARS-CoV-2 main protease (Mpro)–Molecular dynamics, molecular mechanics, and density functional theory investigations

TI Adelusi, AQK Oyedele, OE Monday… - Journal of Molecular …, 2022 - Elsevier
The recent evolution of the SARS-like Coronavirus has ravaged the world. The deadly virus
has claimed over millions of lives across the world and hence highlights the need to develop …

SARS-CoV-2 genomic surveillance in Costa Rica: Evidence of a divergent population and an increased detection of a spike T1117I mutation

JA Molina-Mora, E Cordero-Laurent, A Godínez… - Infection, Genetics and …, 2021 - Elsevier
Genome sequencing is a key strategy in the surveillance of SARS-CoV-2, the virus
responsible for the COVID-19 pandemic. Latin America is the hardest-hit region of the world …