[HTML][HTML] Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Bacterial cellulose-based composites as vehicles for dermal and transdermal drug delivery: a review

S Mohammadi, F Jabbari, V Babaeipour - International Journal of …, 2023 - Elsevier
In recent years, a significant amount of drugs have been taken orally, which are not as
effective as desired. To solve this problem, bacterial cellulose-based dermal/transdermal …

[HTML][HTML] Cubosomes-assisted transdermal delivery of doxorubicin and indocyanine green for chemo-photothermal combination therapy of melanoma

Z Chen, Q Huang, Y Song, X Feng, L Zeng, Z Liu… - Biomedicine & …, 2023 - Elsevier
Melanoma is a highly aggressive form of skin cancer with limited therapeutic options.
Chemo-photothermal combination therapy has demonstrated potential for effectively treating …

Transdermal drug delivery via microneedles for musculoskeletal systems

H Zheng, X Xie, H Ling, X You, S Liang, R Lin… - Journal of Materials …, 2023 - pubs.rsc.org
As the population is ageing and lifestyle is changing, the prevalence of musculoskeletal
(MSK) disorders is gradually increasing with each passing year, posing a serious threat to …

Efficient Loading and Sustained Delivery of Methotrexate Using a Tip-Swellable Microneedle Array Patch for Psoriasis Treatment

P Zhao, Z Li, Z Ling, Y Zheng… - ACS Biomaterials Science …, 2024 - ACS Publications
Methotrexate (MTX), a primary treatment for moderate to severe psoriasis, is limited in
clinical use due to suboptimal results and severe side effects from subcutaneous (SC) …

Transdermal delivery of resveratrol loaded solid lipid nanoparticle as a microneedle patch: a novel approach for the treatment of Parkinson's disease

A Bandiwadekar, J Jose, G Gopan, V Augustin… - Drug delivery and …, 2024 - Springer
Abstract Parkinson's disease (PD), affecting millions of people worldwide and expected to
impact 10 million by 2030, manifests a spectrum of motor and non-motor symptoms linked to …

3D Printing of Biodegradable Polymeric Microneedles for Transdermal Drug Delivery Applications

FK Aldawood, SK Parupelli, A Andar, S Desai - Pharmaceutics, 2024 - mdpi.com
Microneedle (MN) technology is an optimal choice for the delivery of drugs via the
transdermal route, with a minimally invasive procedure. MN applications are varied from …

Novel synergistic approaches of protein delivery through physical enhancement for transdermal microneedle drug delivery: A review

R Chakraborty, N Afrose, K Kuotsu - Journal of Drug Delivery Science and …, 2023 - Elsevier
Innovation in the delivery system is a key tool for increasing the bioavailability of active
pharmaceutical ingredients (API). The oral route is the most promising and convenient route …

Transdermal drug delivery system: current status and clinical application of microneedles

Y Xue, C Chen, X Mi, R Tan, J Wang, S Wu… - ACS Materials …, 2024 - ACS Publications
As a new type of transdermal drug delivery system (TDDS), microneedles have garnered
significant attention for their noninvasiveness, portability, controllable drug administration …

Biomimetic microneedles: Exploring the recent advances on a microfabricated system for precision delivery of drugs, peptides, and proteins

CE Umeyor, V Shelke, A Pol, P Kolekar… - Future Journal of …, 2023 - Springer
Background Despite its popularity, acceptability, and convenience, the oral route is not the
classical route for the administration of all critical bioactives including lipophilic drugs …