Revisiting the neurovascular unit

S Schaeffer, C Iadecola - Nature neuroscience, 2021 - nature.com
The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …

Why is everyone talking about brain state?

AS Greene, C Horien, D Barson, D Scheinost… - Trends in …, 2023 - cell.com
The rapid and coordinated propagation of neural activity across the brain provides the
foundation for complex behavior and cognition. Technical advances across neuroscience …

Deep posteromedial cortical rhythm in dissociation

S Vesuna, IV Kauvar, E Richman, F Gore, T Oskotsky… - Nature, 2020 - nature.com
Advanced imaging methods now allow cell-type-specific recording of neural activity across
the mammalian brain, potentially enabling the exploration of how brain-wide dynamical …

An optimized bioluminescent substrate for non-invasive imaging in the brain

Y Su, JR Walker, MP Hall, MA Klein, X Wu… - Nature Chemical …, 2023 - nature.com
Bioluminescence imaging (BLI) allows non-invasive visualization of cells and biochemical
events in vivo and thus has become an indispensable technique in biomedical research …

Simultaneous cortex-wide fluorescence Ca2+ imaging and whole-brain fMRI

EMR Lake, X Ge, X Shen, P Herman, F Hyder… - Nature …, 2020 - nature.com
Achieving a comprehensive understanding of brain function requires multiple imaging
modalities with complementary strengths. We present an approach for concurrent widefield …

Task-dependent changes in the large-scale dynamics and necessity of cortical regions

L Pinto, K Rajan, B DePasquale, SY Thiberge… - Neuron, 2019 - cell.com
Neural activity throughout the cortex is correlated with perceptual decisions, but inactivation
studies suggest that only a small number of areas are necessary for these behaviors. Here …

Global representations of goal-directed behavior in distinct cell types of mouse neocortex

WE Allen, IV Kauvar, MZ Chen, EB Richman, SJ Yang… - Neuron, 2017 - cell.com
The successful planning and execution of adaptive behaviors in mammals may require long-
range coordination of neural networks throughout cerebral cortex. The neuronal …

Sensory-motor cortices shape functional connectivity dynamics in the human brain

X Kong, R Kong, C Orban, P Wang, S Zhang… - Nature …, 2021 - nature.com
Large-scale biophysical circuit models provide mechanistic insights into the micro-scale and
macro-scale properties of brain organization that shape complex patterns of spontaneous …

Entrainment of arteriole vasomotor fluctuations by neural activity is a basis of blood-oxygenation-level-dependent “resting-state” connectivity

C Mateo, PM Knutsen, PS Tsai, AY Shih, D Kleinfeld - Neuron, 2017 - cell.com
Resting-state signals in blood-oxygenation-level-dependent (BOLD) imaging are used to
parcellate brain regions and define" functional connections" between regions. Yet a …

Ultra-slow oscillations in fMRI and resting-state connectivity: neuronal and vascular contributions and technical confounds

PJ Drew, C Mateo, KL Turner, X Yu, D Kleinfeld - Neuron, 2020 - cell.com
Summary Ultra-slow,∼ 0.1-Hz variations in the oxygenation level of brain blood are widely
used as an fMRI-based surrogate of" resting-state" neuronal activity. The temporal …