[HTML][HTML] Mechanisms of acquired resistance to first-and second-generation EGFR tyrosine kinase inhibitors
Patients with non-small-cell lung cancer (NSCLC) whose tumours harbour activating
mutations within the epidermal growth factor receptor (EGFR) frequently derive significant …
mutations within the epidermal growth factor receptor (EGFR) frequently derive significant …
Comparative review of drug–drug interactions with epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer
ZY Xu, JL Li - OncoTargets and therapy, 2019 - Taylor & Francis
The development of small-molecule tyrosine kinase inhibitors (TKIs) that target the
epidermal growth factor receptor (EGFR) has revolutionized the management of non-small …
epidermal growth factor receptor (EGFR) has revolutionized the management of non-small …
Humour and laughing in patients with prolonged incurable cancer: an ethnographic study in a comprehensive cancer centre
HM Buiting, R de Bree, L Brom, JW Mack… - Quality of Life …, 2020 - Springer
Purpose Most people are familiar with the expression 'laughter is the best medicine'. By
enhancing cognitive flexibility and strengthening relationships, laughter can be considered a …
enhancing cognitive flexibility and strengthening relationships, laughter can be considered a …
Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines
L Zhang, J Li, J Hu, D Li, X Wang, R Zhang, H Zhang… - Lung Cancer, 2017 - Elsevier
Objectives Epithelial growth factor receptor (EGFR) somatic-mutated non-small cell lung
cancer (NSCLC) patients with smoking history always show a poor response to EGFR …
cancer (NSCLC) patients with smoking history always show a poor response to EGFR …
Complex challenges for patients with protracted incurable cancer: an ethnographic study in a comprehensive cancer centre in the Netherlands
HM Buiting, MAC van Ark, O Dethmers, EPE Maats… - BMJ open, 2019 - bmjopen.bmj.com
Objective Advances in oncology increasingly result in protracted disease trajectories for
patients with incurable cancer. In this disease phase, patients are aware of the incurable …
patients with incurable cancer. In this disease phase, patients are aware of the incurable …
[HTML][HTML] High-dose administration of tyrosine kinase inhibitors to improve clinical benefit: A systematic review
SL Gerritse, JBE Janssen, M Labots, R de Vries… - Cancer Treatment …, 2021 - Elsevier
Background Innovative strategies to fully exploit the antitumor activity of multitargeted
tyrosine kinase inhibitors (TKIs) are urgently needed. Higher concentrations of TKIs at their …
tyrosine kinase inhibitors (TKIs) are urgently needed. Higher concentrations of TKIs at their …
Comparative efficacy of second-and subsequent-line treatments for metastatic NSCLC: a fractional polynomials network meta-analysis of cancer immunotherapies
C Schulz, D Gandara, CG Berardo, R Rosenthal… - Clinical Lung Cancer, 2019 - Elsevier
Background Extended onset of treatment effect and longer-term survival with anti–
programmed death-ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) …
programmed death-ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) …
EGFR Mutation Testing of non-squamous NSCLC: Impact and Uptake during Implementation of Testing Guidelines in a Population-Based Registry Cohort from …
Background Since 2013, clinical practice guidelines recommend EGFR mutation testing of
non-squamous NSCLC to select advanced-stage patients for first-line treatment using EGFR …
non-squamous NSCLC to select advanced-stage patients for first-line treatment using EGFR …
Ultra-short-period perioperative pulmonary rehabilitation on short-term outcomes after surgery in smoking patients with lung cancer: A randomized clinical trial
D Han, X Wang, X Sun, Y Cao, C Li… - … Journal of Surgery, 2024 - journals.lww.com
Background: Pulmonary rehabilitation is essential for airway management after thoracic
surgery. Most current pulmonary rehabilitations are composed of 2-4-week exercises, which …
surgery. Most current pulmonary rehabilitations are composed of 2-4-week exercises, which …
Early [18] FDG PET/CT scan predicts tumor response in head and neck squamous cell cancer patients treated with erlotinib adjusted per smoking status
M Porosnicu, A O'Brien Cox, JD Waltonen… - Frontiers in …, 2022 - frontiersin.org
Translational Relevance Evaluation of targeted therapies is urgently needed for the majority
of patients with metastatic/recurrent head and neck squamous cell carcinoma (HNSCC) who …
of patients with metastatic/recurrent head and neck squamous cell carcinoma (HNSCC) who …