Whole flaxseed diet alters estrogen metabolism to promote 2-methoxtestradiol-induced apoptosis in hen ovarian cancer
A Dikshit, K Hales, DB Hales - The Journal of nutritional biochemistry, 2017 - Elsevier
The study reported here demonstrates that a flaxseed-supplemented diet causes ovarian
tumors in the laying hen to undergo apoptosis, resulting in a reduction of tumor burden …
tumors in the laying hen to undergo apoptosis, resulting in a reduction of tumor burden …
Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent manner
A Dikshit, MA Gomes Filho, E Eilati, S McGee… - British Journal of …, 2015 - cambridge.org
The objective of the present study was to find the optimum dose of flaxseed that would
decrease PG and alter oestrogen pathway endpoints implicated in ovarian cancer. In the …
decrease PG and alter oestrogen pathway endpoints implicated in ovarian cancer. In the …
Prolactin signaling drives tumorigenesis in human high grade serous ovarian cancer cells and in a spontaneous fallopian tube derived model
The pathways responsible for tumorigenesis of high grade serous ovarian cancer (HGSOC)
from the fallopian tube epithelium (FTE) are still poorly understood. A human prolactin (PRL) …
from the fallopian tube epithelium (FTE) are still poorly understood. A human prolactin (PRL) …
[HTML][HTML] Differential expression of alpha 2 macroglobulin in response to dietylstilbestrol and in ovarian carcinomas in chickens
W Lim, W Jeong, JH Kim, JY Lee, J Kim… - Reproductive Biology …, 2011 - Springer
Abstract Background Alpha 2 macroglobulin (A2M; also known as ovostatin), a
homotetrameric protein with four disulfide-linked subunits, has the unique feature of …
homotetrameric protein with four disulfide-linked subunits, has the unique feature of …
Interleukin 16 expression changes in association with ovarian malignant transformation
A Yellapa, P Bitterman, S Sharma, AS Guirguis… - American journal of …, 2014 - Elsevier
Objective Long-term unresolved inflammation has been suggested as a risk factor for the
development of various malignancies. The goal of this study was to examine whether the …
development of various malignancies. The goal of this study was to examine whether the …
Minireview: animal models and mechanisms of ovarian cancer development
LK Mullany, JAS Richards - Endocrinology, 2012 - academic.oup.com
Ovarian cancer in women is a complex and deadly disease, where the molecular events that
initiate and control tumor formation remain poorly defined. Therefore, mouse models provide …
initiate and control tumor formation remain poorly defined. Therefore, mouse models provide …
[HTML][HTML] Chicken pleiotrophin: regulation of tissue specific expression by estrogen in the oviduct and distinct expression pattern in the ovarian carcinomas
Pleiotrophin (PTN) is a developmentally-regulated growth factor which is widely distributed
in various tissues and also detected in many kinds of carcinomas. However, little is known …
in various tissues and also detected in many kinds of carcinomas. However, little is known …
Expression of leukocyte inhibitory immunoglobulinlike transcript 3 receptors by ovarian tumors in laying hen model of spontaneous ovarian cancer
MF Khan, JM Bahr, A Yellapa, P Bitterman… - Translational …, 2012 - Elsevier
Attempts to enhance a patient's immune response and ameliorate the poor prognosis of
ovarian cancer (OVCA) have largely been unsuccessful owing to the suppressive tumor …
ovarian cancer (OVCA) have largely been unsuccessful owing to the suppressive tumor …
[HTML][HTML] SERPIND1 affects the malignant biological behavior of epithelial ovarian cancer via the PI3K/AKT pathway: a mechanistic study
Q Guo, L Zhu, C Wang, S Wang, X Nie, J Liu… - Frontiers in …, 2019 - frontiersin.org
Serpin family D member 1 (SERPIND1) belongs to the serine protease inhibitor family. Its
role in cancers has gradually attracted interest from researchers in recent years. However …
role in cancers has gradually attracted interest from researchers in recent years. However …
Differential expression of vitelline membrane outer layer protein 1: hormonal regulation of expression in the oviduct and in ovarian carcinomas from laying hens
Vitelline membrane outer layer protein 1 (VMO1), a basic protein present in the outer layer of
the vitelline membrane of eggs, plays essential roles in separating the yolk from the egg …
the vitelline membrane of eggs, plays essential roles in separating the yolk from the egg …