[HTML][HTML] Comparative transcriptomic study on the ovarian cancer between chicken and human

G Zhu, X Wang, Y Wang, T Huang, X Zhang, J He… - Poultry Science, 2024 - Elsevier
The laying hen is the spontaneous model of ovarian tumor. A comprehensive comparison
based on RNA-seq from hens and women may shed light on the molecular mechanisms of …

[HTML][HTML] Advantages of the avian model for human ovarian cancer

ADM Bernardo, S Thorsteinsdottir… - Molecular and clinical …, 2015 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the most lethal gynecological cancer. Early detection of OC is crucial
for providing efficient treatment, whereas high mortality rates correlate with late detection of …

Characterization of ascites-derived ovarian tumor cells from spontaneously occurring ovarian tumors of the chicken: evidence for E-cadherin upregulation

A Tiwari, JA Hadley, GL Hendricks III, RG Elkin… - PLoS …, 2013 - journals.plos.org
Ovarian cancer, a highly metastatic disease, is the fifth leading cause of cancer-related
deaths in women. Chickens are widely used as a model for human ovarian cancer as they …

Expression of death receptor 6 by ovarian tumors in laying hens, a preclinical model of spontaneous ovarian cancer

A Barua, A Yellapa, JM Bahr, JS Abramowicz… - Translational …, 2012 - Elsevier
Tumor-associated neoangiogenesis and suppression of antitumor immunity are hallmarks of
tumor development and progression. Death receptor 6 (DR6) has been reported to be …

Anti-inflammatory effects of fish oil in ovaries of laying hens target prostaglandin pathways

E Eilati, CC Small, SR McGee, NK Kurrey… - Lipids in health and …, 2013 - Springer
Background An effective way to control cancer is by prevention. Ovarian cancer is the most
lethal gynecological malignancy. Progress in the treatment and prevention of ovarian cancer …

[HTML][HTML] Evaluating the progenitor cells of ovarian cancer: analysis of current animal models

SM King, JE Burdette - BMB reports, 2011 - ncbi.nlm.nih.gov
Serous ovarian cancer is one of the most lethal gynecological malignancies. Progress on
effective diagnostics and therapeutics for this disease are hampered by ambiguity as to the …

Models for measuring metabolic chemical changes in the metastasis of high grade serous ovarian cancer: fallopian tube, ovary, and omentum

H Lusk, JE Burdette, LM Sanchez - Molecular omics, 2021 - pubs.rsc.org
Ovarian cancer (OC) is the most lethal gynecologic malignancy and high grade serous
ovarian cancer (HGSOC) is the most common and deadly subtype, accounting for 70–80 …

Flaxseed Reduces Cancer Risk by Altering Bioenergetic Pathways in Liver: Connecting SAM Biosynthesis to Cellular Energy

WC Weston, KH Hales, DB Hales - Metabolites, 2023 - mdpi.com
This article illustrates how dietary flaxseed can be used to reduce cancer risk, specifically by
attenuating obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD). We …

Distinct expression pattern and post-transcriptional regulation of cell cycle genes in the glandular epithelia of avian ovarian carcinomas

JY Lee, W Jeong, JH Kim, J Kim, FW Bazer, JY Han… - PLoS …, 2012 - journals.plos.org
The cell cycle system is controlled in a timely manner by three groups of cyclins, cyclin
dependent kinases and cyclin dependent kinase inhibitors. Abnormal alterations of cell …

Aquaporin 5 expression is altered in ovarian tumors and ascites-derived ovarian tumor cells in the chicken model of ovarian tumor

A Tiwari, JA Hadley, R Ramachandran - Journal of ovarian research, 2014 - Springer
Abstract Background Aquaporin 5 (AQP5), a member of the aquaporin family of
transmembrane channel proteins, is involved in water transport and cellular proliferation in …