Interplay between inflammation and pathological bone resorption: insights into recent mechanisms and pathways in related diseases for future perspectives

MA Terkawi, G Matsumae, T Shimizu… - International Journal of …, 2022 - mdpi.com
Bone is a mineralized and elastic connective tissue that provides fundamental functions in
the human body, including mechanical support to the muscles and joints, protection of vital …

[HTML][HTML] Emerging nanosonosensitizers augment sonodynamic-mediated antimicrobial therapies

Q Xu, W Xiu, Q Li, Y Zhang, X Li, M Ding, D Yang… - Materials Today Bio, 2023 - Elsevier
With the widespread prevalence of drug-resistant pathogens, traditional antibiotics have
limited effectiveness and do not yield the desired outcomes. Recently, alternative …

Clinical characteristics and risk factors of lower extremity amputation in the diabetic inpatients with foot ulcers

H Gong, Y Ren, Z Li, P Zha, R Bista, Y Li… - Frontiers in …, 2023 - frontiersin.org
Objectives To analyze clinical characteristics of the diabetic inpatients with foot ulcers and
explore the risk factors of lower extremity amputation (LEA) in West China Hospital of …

[PDF][PDF] Diagnosis and treatment modalities for osteomyelitis

Y Jha, K Chaudhary - Cureus, 2022 - cureus.com
Osteomyelitis is an infection-related inflammatory disease of the bones. Imaging and
laboratory results are typically used to support a clinical diagnosis of osteomyelitis. Microbial …

Multicenter evaluation of the BIOFIRE Joint Infection Panel for the detection of bacteria, yeast, and AMR genes in synovial fluid samples

J Esteban, L Salar-Vidal, BH Schmitt… - Journal of clinical …, 2023 - Am Soc Microbiol
The bioMérieux BIOFIRE Joint Infection (JI) Panel is a multiplex in vitro diagnostic test for the
simultaneous and rapid (~ 1 h) detection of 39 potential pathogens and antimicrobial …

Did Saint Leonard suffer from Madura foot at the time of death? Infectious disease diagnosis by paleo-proteotyping

P Charlier, J Armengaud - Journal of Infection, 2024 - journalofinfection.com
Leonard was one of the most renowned saints during the Western Middle Ages. His
biography, written in the 11th century, reports that he was a noble man converted to …

Current application and future perspectives of antimicrobial degradable bone substitutes for chronic osteomyelitis

C Jiang, G Zhu, Q Liu - Frontiers in Bioengineering and Biotechnology, 2024 - frontiersin.org
Chronic osteomyelitis remains a persistent challenge for the surgeons due to its refractory
nature. Generally, treatment involves extensive debridement of necrotic bone, filling of dead …

Inflammatory Microenvironment‐Responsive Hydrogels Enclosed with Quorum Sensing Inhibitor for Treating Post‐Traumatic Osteomyelitis

W Zhang, H Lu, W Zhang, J Hu, Y Zeng, H Hu… - Advanced …, 2024 - Wiley Online Library
Non‐antibiotic strategies are desperately needed to treat post‐traumatic osteomyelitis (PTO)
due to the emergence of superbugs, complex inflammatory microenvironments, and greatly …

Development of a multiplex Loop-Mediated Isothermal Amplification (LAMP) for the diagnosis of bacterial periprosthetic joint infection

WS Jang, S Park, JH Bae, SY Yoon, CS Lim, MC Cho - Plos one, 2024 - journals.plos.org
Background Periprosthetic joint infection (PJI) is one of the most serious and debilitating
complications that can occur after total joint arthroplasty. Therefore, early diagnosis and …

Prophylactic Effects of NFκB Essential Modulator–Binding Domain Peptides on Bone Infection: An Experimental Study in a Rabbit Model

WJ Wu, CL Xia, SJ Ou, Y Yang, XZ Zhou… - Journal of …, 2022 - Taylor & Francis
Introduction Osteomyelitis is characterized by intensive inflammatory bone disease and
remains a clinical challenge in orthopedic surgery, despite the advances made in medical …