[HTML][HTML] Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement

V Aggarwal, HS Tuli, M Tania, S Srivastava… - Seminars in cancer …, 2022 - Elsevier
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …

The new RNA world: growing evidence for long noncoding RNA functionality

A Jandura, HM Krause - Trends in Genetics, 2017 - cell.com
The past decade has seen a major increase in the study of noncoding RNAs (ncRNAs).
However, there remains a great deal of confusion and debate over the levels of functionality …

The role of non-coding RNAs in ABC transporters regulation and their clinical implications of multidrug resistance in cancer

Y Wang, Y Wang, Z Qin, S Cai, L Yu… - Expert opinion on drug …, 2021 - Taylor & Francis
Introduction Multi-drug resistance (MDR) is a hindrance toward the successful treatment of
cancers. The primary mechanism that gives rise to acquired chemoresistance is the …

[HTML][HTML] Mammalian circular RNAs result largely from splicing errors

C Xu, J Zhang - Cell reports, 2021 - cell.com
Ubiquitous in eukaryotes, circular RNAs (circRNAs) comprise a large class of mostly non-
coding RNAs produced by back-splicing. Although some circRNAs have demonstrated …

[HTML][HTML] Non-coding RNAs in breast cancer: intracellular and intercellular communication

CM Klinge - Non-coding RNA, 2018 - mdpi.com
Non-coding RNAs (ncRNAs) are regulators of intracellular and intercellular signaling in
breast cancer. ncRNAs modulate intracellular signaling to control diverse cellular processes …

Rapid and accurate identification of ribosomal RNA sequences via deep learning

ZL Deng, PC Münch, R Mreches… - Nucleic acids …, 2022 - academic.oup.com
Advances in transcriptomic and translatomic techniques enable in-depth studies of RNA
activity profiles and RNA-based regulatory mechanisms. Ribosomal RNA (rRNA) sequences …

[HTML][HTML] Regulatory non-coding RNAs: a new frontier in regulation of plant biology

S Bhogireddy, SK Mangrauthia, R Kumar… - Functional & Integrative …, 2021 - Springer
Beyond the most crucial roles of RNA molecules as a messenger, ribosomal, and transfer
RNAs, the regulatory role of many non-coding RNAs (ncRNAs) in plant biology has been …

Regulatory activity is the default DNA state in eukaryotes

I Luthra, C Jensen, XE Chen, AL Salaudeen… - Nature Structural & …, 2024 - nature.com
Genomes encode for genes and non-coding DNA, both capable of transcriptional activity.
However, unlike canonical genes, many transcripts from non-coding DNA have limited …

Navigating the pitfalls of mapping DNA and RNA modifications

Y Kong, EA Mead, G Fang - Nature Reviews Genetics, 2023 - nature.com
Chemical modifications to nucleic acids occur across the kingdoms of life and carry
important regulatory information. Reliable high-resolution mapping of these modifications is …