[HTML][HTML] Transcriptional riboswitches integrate timescales for bacterial gene expression control

CE Scull, SS Dandpat, RA Romero… - Frontiers in molecular …, 2021 - frontiersin.org
Transcriptional riboswitches involve RNA aptamers that are typically found in the 5′
untranslated regions (UTRs) of bacterial mRNAs and form alternative secondary structures …

Diverse and pervasive subcellular distributions for both coding and long noncoding RNAs

R Wilk, J Hu, D Blotsky, HM Krause - Genes & development, 2016 - genesdev.cshlp.org
In a previous analysis of 2300 mRNAs via whole-mount fluorescent in situ hybridization in
cellularizing Drosophila embryos, we found that 70% of the transcripts exhibited some form …

[HTML][HTML] Long non-coding RNAs in cardiovascular diseases: potential function as biomarkers and therapeutic targets of exercise training

CCM Correia, LF Rodrigues, BR de Avila Pelozin… - Non-coding RNA, 2021 - mdpi.com
Despite advances in treatments and therapies, cardiovascular diseases (CVDs) remain one
of the leading causes of death worldwide. The discovery that most of the human genome …

Regulation of cGAS activity by RNA‐modulated phase separation

S Chen, M Rong, Y Lv, D Zhu, Y Xiang - EMBO reports, 2023 - embopress.org
Abstract Cyclic GMP‐AMP synthase (cGAS) is a double‐stranded DNA (dsDNA) sensor that
functions in the innate immune system. Upon binding dsDNA, cGAS and dsDNA form phase …

[HTML][HTML] High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA

ZW Mo, YM Peng, YX Zhang, Y Li, BA Kang… - … and Targeted Therapy, 2023 - nature.com
Normal high-density lipoprotein (nHDL) can induce angiogenesis in healthy individuals.
However, HDL from patients with coronary artery disease undergoes various modifications …

EPC‐derived exosomes promote osteoclastogenesis through Lnc RNA‐MALAT 1

Y Cui, S Fu, D Sun, J Xing, T Hou… - Journal of Cellular and …, 2019 - Wiley Online Library
Bone repair involves bone resorption through osteoclastogenesis and the stimulation of
neovascularization and osteogenesis by endothelial progenitor cells (EPC s). However, the …

[HTML][HTML] Epigenetic landscape during coronavirus infection

A Schäfer, RS Baric - Pathogens, 2017 - mdpi.com
Coronaviruses (CoV) comprise a large group of emerging human and animal pathogens,
including the highly pathogenic severe acute respiratory syndrome coronavirus (SARS-CoV) …

[HTML][HTML] Frameworks for targeting RNA with small molecules

AU Juru, AE Hargrove - Journal of Biological Chemistry, 2021 - ASBMB
Since the characterization of mRNA in 1961, our understanding of the roles of RNA
molecules has significantly grown. Beyond serving as a link between DNA and proteins …

Global identification of mRNA-interacting circular RNAs by CLiPPR-Seq

S Singh, S Shyamal, A Das, AC Panda - Nucleic acids research, 2024 - academic.oup.com
Although the functional role of circular RNA (circRNA) interaction with microRNAs and
proteins has been studied extensively, circRNA interactions with the protein-coding mRNAs …

[HTML][HTML] Role of non-coding-RNAs in response to environmental stressors and consequences on human health

V Miguel, S Lamas, C Espinosa-Diez - Redox biology, 2020 - Elsevier
Environmental risk factors, including physicochemical agents, noise and mental stress, have
a considerable impact on human health. This environmental exposure may lead to …