Role of noncoding RNAs in the pathogenesis of abdominal aortic aneurysm: possible therapeutic targets?
Abdominal aortic aneurysm (AAA) is a local dilatation of the abdominal aortic vessel wall
and is among the most challenging cardiovascular diseases as without urgent surgical …
and is among the most challenging cardiovascular diseases as without urgent surgical …
rDNA magnification is a unique feature of germline stem cells
JO Nelson, T Kumon… - Proceedings of the …, 2023 - National Acad Sciences
Ribosomal DNA (rDNA) encodes ribosomal RNA and exists as tandem repeats of hundreds
of copies in the eukaryotic genome to meet the high demand of ribosome biogenesis …
of copies in the eukaryotic genome to meet the high demand of ribosome biogenesis …
Extracellular vesicles in tissue engineering: biology and engineered strategy
Z Pan, W Sun, Y Chen, H Tang, W Lin… - Advanced …, 2022 - Wiley Online Library
Extracellular vesicles (EVs), acting as an important ingredient of intercellular communication
through paracrine actions, have gained tremendous attention in the field of tissue …
through paracrine actions, have gained tremendous attention in the field of tissue …
Sequence determinants for nuclear retention and cytoplasmic export of mRNAs and lncRNAs
AF Palazzo, ES Lee - Frontiers in genetics, 2018 - frontiersin.org
Eukaryotes are divided into two major compartments: the nucleus where RNA is synthesized
and processed, and the cytoplasm, where mRNA is translated into proteins. Although many …
and processed, and the cytoplasm, where mRNA is translated into proteins. Although many …
What are the distinguishing features and size requirements of biomolecular condensates and their implications for RNA-containing condensates?
JD Forman-Kay, JA Ditlev, ML Nosella, HO Lee - RNA, 2022 - rnajournal.cshlp.org
Exciting recent work has highlighted that numerous cellular compartments lack
encapsulating lipid bilayers (often called “membraneless organelles”), and that their …
encapsulating lipid bilayers (often called “membraneless organelles”), and that their …
CircTHBS1 drives gastric cancer progression by increasing INHBA mRNA expression and stability in a ceRNA-and RBP-dependent manner
S Qiu, B Li, Y Xia, Z Xuan, Z Li, L Xie, C Gu, J Lv… - Cell death & …, 2022 - nature.com
Circular RNAs (circRNAs) play vital regulatory roles in the progression of multiple cancers.
In our study, transcriptome analysis and self-organizing maps (SOM) were applied to screen …
In our study, transcriptome analysis and self-organizing maps (SOM) were applied to screen …
Gene-specific control of tRNA expression by RNA polymerase II
Increasing evidence suggests that tRNA levels are dynamically and specifically regulated in
response to internal and external cues to modulate the cellular translational program …
response to internal and external cues to modulate the cellular translational program …
Long non-coding RNAs: mechanisms, experimental, and computational approaches in identification, characterization, and their biomarker potential in cancer
A Chowdhary, V Satagopam, R Schneider - Frontiers in Genetics, 2021 - frontiersin.org
Long non-coding RNAs are diverse class of non-coding RNA molecules> 200 base pairs of
length having various functions like gene regulation, dosage compensation, epigenetic …
length having various functions like gene regulation, dosage compensation, epigenetic …
Long noncoding RNAs: a missing link in osteoporosis
AM Silva, SR Moura, JH Teixeira, MA Barbosa… - Bone research, 2019 - nature.com
Osteoporosis is a systemic disease that results in loss of bone density and increased
fracture risk, particularly in the vertebrae and the hip. This condition and associated …
fracture risk, particularly in the vertebrae and the hip. This condition and associated …
Translational perspective on epigenetics in cardiovascular disease
A plethora of environmental and behavioral factors interact, resulting in changes in gene
expression and providing a basis for the development and progression of cardiovascular …
expression and providing a basis for the development and progression of cardiovascular …