Long-read sequencing–a powerful tool in viral transcriptome research
Long-read sequencing (LRS) has become increasingly popular due to its strengths in de
novo assembly and in resolving complex DNA regions as well as in determining full-length …
novo assembly and in resolving complex DNA regions as well as in determining full-length …
Unlocking the potential of chemically modified peptide nucleic acids for RNA-based therapeutics
SP Pradeep, S Malik, FJ Slack, R Bahal - RNA, 2023 - rnajournal.cshlp.org
RNA therapeutics have emerged as next-generation therapy for the treatment of many
diseases. Unlike small molecules, RNA targeted drugs are not limited by the availability of …
diseases. Unlike small molecules, RNA targeted drugs are not limited by the availability of …
Cryo-EM structures of human RNA polymerase I
Abstract RNA polymerase I (Pol I) specifically synthesizes ribosomal RNA. Pol I upregulation
is linked to cancer, while mutations in the Pol I machinery lead to developmental disorders …
is linked to cancer, while mutations in the Pol I machinery lead to developmental disorders …
Bacterial antisense RNAs are mainly the product of transcriptional noise
V Lloréns-Rico, J Cano, T Kamminga, R Gil… - Science …, 2016 - science.org
cis-Encoded antisense RNAs (asRNAs) are widespread along bacterial transcriptomes.
However, the role of most of these RNAs remains unknown, and there is an ongoing …
However, the role of most of these RNAs remains unknown, and there is an ongoing …
Trees, fungi and bacteria: tripartite metatranscriptomics of a root microbiome responding to soil contamination
E Gonzalez, FE Pitre, AP Pagé, J Marleau… - Microbiome, 2018 - Springer
Background One method for rejuvenating land polluted with anthropogenic contaminants is
through phytoremediation, the reclamation of land through the cultivation of specific crops …
through phytoremediation, the reclamation of land through the cultivation of specific crops …
New insights into the implication of epigenetic alterations in the EMT of triple negative breast cancer
Breast cancer is the most common cancer and leading cause of cancer death among
women worldwide, encompassing a wide heterogeneity of subtypes with different clinical …
women worldwide, encompassing a wide heterogeneity of subtypes with different clinical …
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
Early-stage detection of leukemia is a critical determinant for successful treatment of the
disease and can increase the survival rate of leukemia patients. The factors limiting the …
disease and can increase the survival rate of leukemia patients. The factors limiting the …
Non-coding RNAs in regulating plaque progression and remodeling of extracellular matrix in atherosclerosis
Non-coding RNAs (ncRNAs) regulate cell proliferation, migration, differentiation,
inflammation, metabolism of clinically important biomolecules, and other cellular processes …
inflammation, metabolism of clinically important biomolecules, and other cellular processes …
Calcium/calmodulin-mediated defense signaling: What is looming on the horizon for AtSR1/CAMTA3-mediated signaling in plant immunity
Calcium (Ca2+) signaling in plant cells is an essential and early event during plant-microbe
interactions. The recognition of microbe-derived molecules activates Ca2+ channels or …
interactions. The recognition of microbe-derived molecules activates Ca2+ channels or …
[HTML][HTML] Cancer driver gene and non-coding RNA alterations as biomarkers of brain metastasis in lung cancer: a review of the literature
Brain metastasis (BM) is the most common event in patients with lung cancer. Despite
multimodal treatments and advances in systemic therapies, development of BM remains one …
multimodal treatments and advances in systemic therapies, development of BM remains one …