Intercellular communication is a key feature of cancer progression and metastasis.
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …

Metastatic progression combined with non-responsiveness towards systemic therapy often
shapes the course of disease for cancer patients and commonly determines its lethal …

Transforming growth factor-β (TGF-β) signaling shows important roles in both physiology
and pathology, especially in the progression of inflammatory diseases including cancer …

Although immunotherapy has made breakthrough progress, its efficacy in solid tumours
remains unsatisfactory. Exosomes are the main type of extracellular vesicles that can deliver …

Breast cancer has been the most common cancer in women worldwide, and metastasis is
the leading cause of death from breast cancer. Even though the study of breast cancer …

Extracellular vesicles (EVs) are natural carriers for intercellular transfer of bioactive
molecules, which are harnessed for wide biomedical applications. However, a facile yet …

Extracellular vesicles (EVs) encompass a diverse set of membrane-derived particles
released from cells and are found in numerous biological matrices and the extracellular …

Head and neck squamous cell carcinoma is the sixth most common cancer worldwide and
has high heterogeneity and unsatisfactory outcomes. To better characterize the tumor …

The proliferation and function of immune cells are often inhibited by the binding of
programmed cell-death ligand 1 (PD-L1) to programmed cell-death 1 (PD-1). So far, many …

Tumor cells actively incorporate molecules (eg, proteins, lipids, RNA) into particles named
extracellular vesicles (EVs). Several groups have demonstrated that EVs can be transferred …