Early fibrinogen degradation coagulopathy is predictive of parenchymal hematomas in cerebral rt-PA thrombolysis: a study of 157 cases

P Trouillas, L Derex, F Philippeau, N Nighoghossian… - Stroke, 2004 - Am Heart Assoc
Background—Little is known about the coagulation factors as predictors of cerebral bleeding
in rt-PA thrombolysis. The aim of this study was to determine what early coagulation …

Baseline blood pressure but not early computed tomography changes predicts major hemorrhage after streptokinase in acute ischemic stroke

AK Gilligan, R Markus, S Read, V Srikanth, T Hirano… - Stroke, 2002 - Am Heart Assoc
Background and Purpose—Intracerebral hemorrhage is the most serious complication of
thrombolytic therapy for stroke. We explored factors associated with this complication in the …

Telestroke—the promise and the challenge. Part one: growth and current practice

F Akbik, JA Hirsch, RV Chandra, D Frei… - Journal of …, 2017 - jnis.bmj.com
Acute ischemic stroke remains a major public health concern, with low national treatment
rates for the condition, demonstrating a disconnection between the evidence of treatment …

Thrombolysis for acute stroke in routine clinical practice

DM Bravata, N Kim, J Concato… - Archives of Internal …, 2002 - jamanetwork.com
Background Studies have demonstrated that thrombolytic therapy for acute stroke can be
given safely and effectively in study settings with experienced clinicians, but the patient …

重组组织型纤溶酶原激活剂早期静脉溶栓对急性脑梗死的疗效

曾红, 樊琨, 王克英, 左鹰, 王沈燕, 胡南, 李学英… - 中华神经科杂志, 2006 - cqvip.com
目的评价重组组织型纤溶酶原激活剂(rt-PA) 6 h 内静脉溶栓治疗急性脑梗死的疗效及剂量.
方法将符合入选标准的206 例患者随机分为A, B, C 组, A 组rt-PA 0.9 mg/kg, B 组rt-PA 0.7 …

Hemorrhagic complications after off-label thrombolysis for ischemic stroke

A Aleu, P Mellado, C Lichy, M Köhrmann… - Stroke, 2007 - Am Heart Assoc
Background and Purpose—Only 2% to 4% of patients with acute ischemic stroke receive
thrombolytic therapy resulting from the current strict inclusion criteria among other issues …

Ischemic stroke therapy

C Stapf, JP Mohr - Annual review of medicine, 2002 - annualreviews.org
▪ Abstract Stroke is the most common life-threatening neurologic disease and the leading
cause of serious long-term disability. The advent of new treatment options for selected …

Symptomatic intracerebral hemorrhage among eligible warfarin-treated patients receiving intravenous tissue plasminogen activator for acute ischemic stroke

S Prabhakaran, J Rivolta, JR Vieira… - Archives of …, 2010 - jamanetwork.com
Objective To determine whether warfarin-treated patients with an international normalized
ratio less than 1.7 who receive intravenous tissue plasminogen activator for acute ischemic …

Thrombolytic therapy for acute ischemic stroke

JO Blakeley, RH Llinas - Journal of the Neurological Sciences, 2007 - Elsevier
The treatment of acute stroke changed dramatically since the publication of the NINDS trail
for IV rt-PA for acute stroke. While this was not the first trial, it was the first positive trial …

Clinical policy: use of intravenous tPA for the management of acute ischemic stroke in the emergency department

American College of Emergency … - Annals of …, 2013 - pubmed.ncbi.nlm.nih.gov
This policy was developed by a joint writing panel of the American College of Emergency
Physicians and the American Academy of Neurology. The panel reviewed the literature to …