Introduction. Quick thrombolysis after stroke improved clinical outcomes. The study objective
was to shorten door‐to‐needle time for thrombolysis. Methods. After identifying the sources …

Symptomatic intracerebral hemorrhage following intravenous thrombolysis for stroke
occurred in 6% of patients, with a 3% risk of death during the original NINDS study. 1 Higher …

Background and purpose: As patients with abnormal baseline coagulation were excluded
from the large randomized trials, the safety of intravenous thrombolysis after ischaemic …

Background: To determine the frequency and predictors of symptomatic intracerebral
hemorrhage (SICH) in patients treated with recombinant tissue plasminogen activator (rt …

This article about treatment and prevention of stroke is part of the Antithrombotic and
Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical …

Nontraumatic or spontaneous intracerebral hemorrhage (ICH) is defined as spontaneous
bleeding into the parenchyma of the brain that may also extend into the ventricles, and …

STUDY OBJECTIVE: Administration of tissue plasminogen activator (tPA) for acute ischemic
stroke remains controversial in community practice. Well-organized hierarchic systems of …

Blood pressure (BP) is the major determinant of cerebral perfusion yet blood pressure
management in acute stroke is complex and controversial. Optimized blood pressure …

In this Leading opinion we summarise the observational evidence endorsing current
guidelines that advocate effective blood pressure control before and during an rtPA infusion …

Background: The influence of antiplatelet agents (AP) in the development of a symptomatic
intracranial haemorrhage (SICH) after intravenous rt-PA is not well known. We assessed the …