[HTML][HTML] Hyperglycemia and oxidative stress: An integral, updated and critical overview of their metabolic interconnections

P González, P Lozano, G Ros, F Solano - International Journal of …, 2023 - mdpi.com
This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

[HTML][HTML] Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives

DM Tanase, EM Gosav, MI Anton, M Floria… - Biomolecules, 2022 - mdpi.com
Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …

[HTML][HTML] Protective effects of curcumin in cardiovascular diseases—Impact on oxidative stress and mitochondria

FF Cox, A Misiou, A Vierkant, N Ale-Agha, M Grandoch… - Cells, 2022 - mdpi.com
Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …

Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance

S Mirzaei, AT Mohammadi, MH Gholami… - Pharmacological …, 2021 - Elsevier
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

[HTML][HTML] Curcumin delivery mediated by bio-based nanoparticles: a review

M Moballegh Nasery, B Abadi, D Poormoghadam… - Molecules, 2020 - mdpi.com
Todays, nano-pharmaceutics is emerging as an important field of science to develop and
improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the …

Status and future scope of plant-based green hydrogels in biomedical engineering

R Mohammadinejad, H Maleki, E Larraneta… - Applied Materials …, 2019 - Elsevier
Hydrogels are the most iconic class of soft materials, and since their first report in the
literature, they have attracted the attention of uncountable researchers. Over the past two …

[HTML][HTML] Nrf2 regulation by curcumin: molecular aspects for therapeutic prospects

SH Shahcheraghi, F Salemi, N Peirovi, J Ayatollahi… - Molecules, 2021 - mdpi.com
Nuclear factor erythroid 2 p45-related factor (2Nrf2) is an essential leucine zipper protein
(bZIP) that is primarily located in the cytoplasm under physiological conditions. Nrf2 …

Targeting Nrf2 in ischemia-reperfusion alleviation: From signaling networks to therapeutic targeting

M Sadrkhanloo, M Entezari, S Orouei, A Zabolian… - Life Sciences, 2022 - Elsevier
The nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator of redox balance
and it responds to various cell stresses that oxidative stress is the most well-known one. The …

Targeting Nrf2/Keap1 signaling pathway by bioactive natural agents: Possible therapeutic strategy to combat liver disease

R Jayasuriya, U Dhamodharan, D Ali, K Ganesan, B Xu… - Phytomedicine, 2021 - Elsevier
Background Nuclear factor erythroid 2-related factor (Nrf2), a stress-activated transcription
factor, has been documented to induce a defense mechanism against oxidative stress …