The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease

A Odermatt - American Journal of Physiology-Renal …, 2011 - journals.physiology.org
The Western-style diet is characterized by its highly processed and refined foods and high
contents of sugars, salt, and fat and protein from red meat. It has been recognized as the …

Metabolic abnormalities in diabetes and kidney disease: role of uremic toxins

L Koppe, D Fouque, CO Soulage - Current Diabetes Reports, 2018 - Springer
Abstract Purpose of Review Chronic kidney disease (CKD) is characterized by the
accumulation of uremic retention solutes (URS) and is associated with perturbations of …

Sustained antidiabetic effects of a berberine-containing Chinese herbal medicine through regulation of hepatic gene expression

HL Zhao, Y Sui, CF Qiao, KY Yip, RKK Leung… - Diabetes, 2012 - Am Diabetes Assoc
Diabetes and obesity are complex diseases associated with insulin resistance and fatty liver.
The latter is characterized by dysregulation of the Akt, AMP-activated protein kinase (AMPK) …

Diabetes and cancer: the mechanistic implications of epidemiological analyses from the Hong Kong Diabetes Registry

X Yang, WY So, RCW Ma, APS Kong… - Diabetes/metabolism …, 2012 - Wiley Online Library
Diabetes is a disorder of energy metabolism associated with increased cancer risk, but the
underlying mechanism is poorly understood. In a prospective cohort of patients enrolled in …

[HTML][HTML] Advanced oxidation protein products promote NADPH oxidase-dependent β-cell destruction and dysfunction through the Bcl-2/Bax apoptotic pathway

M Liang, A Li, A Lou, X Zhang, Y Chen, L Yang… - Laboratory …, 2017 - nature.com
The accumulation of plasma advanced oxidation protein products (AOPPs) has been linked
with diverse disorders, including diabetes, chronic kidney disease, obesity, and metabolic …

Additive interaction between the renin-angiotensin system and lipid metabolism for cancer in type 2 diabetes

X Yang, H Zhao, Y Sui, RCW Ma, WY So, GTC Ko… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Clinical and experimental studies suggest cross-talk between lipid metabolism
and the renin-angiotensin system (RAS) in atherogenesis. The aim of this study was to …

Drug–subphenotype interactions for cancer in type 2 diabetes mellitus

X Yang, HM Lee, JCN Chan - Nature Reviews Endocrinology, 2015 - nature.com
On the basis of data obtained from a prospective cohort of Chinese patients with type 2
diabetes mellitus (T2DM), we discuss cancer subphenotypes (risk factors) in patients with …

Impact of fructose diet and renal failure on the function of pancreatic islets

M Pokrywczynska, M Flisinski, A Jundzill… - Pancreas, 2014 - journals.lww.com
Objectives This study was designed to evaluate the impact of fructose-rich diet and chronic
kidney disease (CKD) on the in vitro function of pancreatic islets. Methods Fifty-four rats …

Understanding the effects of chronic kidney disease on cardiovascular risk: are there lessons to be learnt from healthy kidney donors?

WE Moody, CD Chue, NG Inston, NC Edwards… - Journal of human …, 2012 - nature.com
Chronic kidney disease (CKD) is now a recognized global public health problem. It is highly
prevalent and strongly associated with hypertension and cardiovascular disease (CVD); far …

Lipid partitioning after uninephrectomy

HL Zhao, Y Sui, L He, J Guan, SJ Xiao, DR Zhong… - Acta …, 2011 - Springer
This longitudinal study addressed the sequential events and metabolic consequences of
lipid partitioning following uninephrectomy. Adult male Sprague–Dawley rats were …