Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …
Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders
A Annamneedi, C Gora, A Dudas… - British journal of …, 2023 - Wiley Online Library
Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped …
core symptoms: deficits in social interaction and communication, and stereotyped …
[HTML][HTML] Modulation of social behavior by distinct vasopressin sources
The neuropeptide arginine-vasopressin (AVP) is well known for its peripheral effects on
blood pressure and antidiuresis. However, AVP also modulates various social and anxiety …
blood pressure and antidiuresis. However, AVP also modulates various social and anxiety …
[HTML][HTML] Role of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin
The psychedelic lysergic acid diethylamide (LSD) has experienced a revival in research,
including clinical trials that evaluate LSD-assisted psychotherapy. LSD induces perceptual …
including clinical trials that evaluate LSD-assisted psychotherapy. LSD induces perceptual …
[HTML][HTML] Effects of intranasal administration of oxytocin and vasopressin on social cognition and potential routes and mechanisms of action
S Yao, KM Kendrick - Pharmaceutics, 2022 - mdpi.com
Acute and chronic administration of intranasal oxytocin and vasopressin have been
extensively utilized in both animal models and human preclinical and clinical studies over …
extensively utilized in both animal models and human preclinical and clinical studies over …
[HTML][HTML] Oxytocin and related peptide hormones: Candidate anti-inflammatory therapy in early stages of sepsis
SF Mehdi, S Pusapati, RR Khenhrani… - Frontiers in …, 2022 - frontiersin.org
Sepsis is a potentially life-threatening systemic inflammatory syndrome characterized by
dysregulated host immunological responses to infection. Uncontrolled immune cell …
dysregulated host immunological responses to infection. Uncontrolled immune cell …
Linking oxytocin and arginine vasopressin signaling abnormalities to social behavior impairments in Prader-Willi syndrome
Prader-Willi syndrome (PWS) is a genetic neurodevelopmental disorder. Global
hypothalamic dysfunction is a core feature of PWS and has been implicated as a driver of …
hypothalamic dysfunction is a core feature of PWS and has been implicated as a driver of …
Oxytocin administration enhances pleasantness and neural responses to gentle stroking but not moderate pressure social touch by increasing peripheral …
Y Chen, H Zou, X Hou, C Lan, J Wang, Y Qing, W Chen… - Elife, 2023 - elifesciences.org
Background: Social touch constitutes a key component of human social relationships,
although in some conditions with social dysfunction, such as autism, it can be perceived as …
although in some conditions with social dysfunction, such as autism, it can be perceived as …
Socio-behavioral dysfunction in disorders of hypothalamic-pituitary involvement: The potential role of disease-induced oxytocin and vasopressin signaling deficits
L Clarke, O Zyga, PL Pineo-Cavanaugh, M Jeng… - Neuroscience & …, 2022 - Elsevier
Disorders involving hypothalamic and pituitary (HPIT) structures—including
craniopharyngioma, Langerhans cell histiocytosis, and intracranial germ cell tumors—can …
craniopharyngioma, Langerhans cell histiocytosis, and intracranial germ cell tumors—can …
Photoswitchable Probes of Oxytocin and Vasopressin
U Wirth, K Raabe, P Kalaba, E Keimpema… - Journal of Medicinal …, 2023 - ACS Publications
Oxytocin (OT) and vasopressin (VP) are related neuropeptides that regulate many biological
processes. In humans, OT and VP act via four G protein-coupled receptors, OTR, V1aR …
processes. In humans, OT and VP act via four G protein-coupled receptors, OTR, V1aR …