Hereditary prostate cancer: clinical aspects

O Bratt - The Journal of urology, 2002 - auajournals.org
Purpose: We review the current epidemiological and genetic knowledge regarding
hereditary prostate cancer, and outline its clinical implications. Materials and Methods …

Expectant management for men with early stage prostate cancer

CP Filson, LS Marks, MS Litwin - CA: a cancer journal for …, 2015 - Wiley Online Library
Answer questions and earn CME/CNE Since the dissemination of prostate‐specific antigen
screening, most men with prostate cancer are now diagnosed with localized, low‐risk …

β-Catenin-related anomalies in apoptosis-resistant and hormone-refractory prostate cancer cells

A de la Taille, MA Rubin, MW Chen, F Vacherot… - Clinical Cancer …, 2003 - AACR
Purpose: β-Catenin is a critical end component of the wnt signaling pathway that regulates
cell growth, apoptosis, and migratory behavior in response to intercellular adhesion …

LDA vs. QDA for FT-MIR prostate cancer tissue classification

LFS Siqueira, RFA Júnior, AA de Araújo… - Chemometrics and …, 2017 - Elsevier
Discrimination/classification of biological material a ta molecular level is one of the key aims
of chemometrics applied to biospectroscopic data. Two discriminant functions, namely …

Young-age prostate cancer

S Hussein, S Satturwar, T Van der Kwast - Journal of clinical pathology, 2015 - jcp.bmj.com
Although prostate cancer is a disease of the elderly, its diagnosis is not uncommonly made
in men younger than 55 years. Both ethnic, familial and genetic factors play a role in the …

Early onset prostate cancer has a significant genetic component

EM Lange, CA Salinas, KA Zuhlke, AM Ray… - The …, 2012 - Wiley Online Library
BACKGROUND Prostate cancer (PCa) affects more than 190,000 men each year with∼
10% of men diagnosed at≤ 55 years, that is, early onset (EO) PCa. Based on historical …

Family history of prostate cancer and obesity in relation to high‐grade disease and extraprostatic extension in young men with prostate cancer

S Rohrmann, WW Roberts, PC Walsh, EA Platz - The Prostate, 2003 - Wiley Online Library
Background Little is known about predictors of prostate cancer severity in young men.
Therefore, we examined whether family history and obesity influence risk of high‐grade …

Temporarily deferred therapy (watchful waiting) for men younger than 70 years and with low-risk localized prostate cancer in the prostate-specific antigen era

CA Carter, T Donahue, L Sun, H Wu… - Journal of clinical …, 2003 - ascopubs.org
Purpose: Watchful waiting (WW) is an acceptable strategy for managing prostate cancer
(PC) in older men. Prostate-specific antigen (PSA) testing has resulted in a stage migration …

Genome‐wide scan of Swedish families with hereditary prostate cancer: suggestive evidence of linkage at 5q11. 2 and 19p13. 3

F Wiklund, EM Gillanders, JA Albertus, A Bergh… - The …, 2003 - Wiley Online Library
BACKGROUND Prostate cancer (CaP) is a common disorder with multiple genetic and
environmental factors contributing to the disease. CaP susceptibility loci can be identified …

Genome-wide association scan for variants associated with early-onset prostate cancer

EM Lange, AM Johnson, Y Wang, KA Zuhlke, Y Lu… - PloS one, 2014 - journals.plos.org
Prostate cancer is the most common non-skin cancer and the second leading cause of
cancer related mortality for men in the United States. There is strong empirical and …