Lung cancer associated with combustion particles and fine particulate matter (PM2. 5)-The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon …

JA Holme, J Vondráček, M Machala… - Biochemical …, 2023 - Elsevier
Air pollution is the leading cause of lung cancer after tobacco smoking, contributing to 20%
of all lung cancer deaths. Increased risk associated with living near trafficked roads …

Cigarette smoke-induced galectin-3 as a diagnostic biomarker and therapeutic target in lung tissue remodeling

JR Sharma, A Dubey, UCS Yadav - Life Sciences, 2024 - Elsevier
Abstract Galectin-3 (Gal-3), a multifunctional carbohydrate-binding lectin, has emerged as a
key player in various biological processes including inflammation, cancer, cardiovascular …

[HTML][HTML] Immunomodulation exerted by galectins: a land of opportunity in rare cancers

L Díaz-Alvarez, GI López-Cortés… - Frontiers in …, 2023 - frontiersin.org
Rare cancers represent only 5% of newly diagnosed malignancies. However, in some
cases, they account for up to 50% of the deaths attributed to cancer in their corresponding …

[HTML][HTML] Galectins in epithelial-mesenchymal transition: roles and mechanisms contributing to tissue repair, fibrosis and cancer metastasis

E Perez-Moreno, C Oyanadel, A de la Peña… - Biological Research, 2024 - Springer
Galectins are soluble glycan-binding proteins that interact with a wide range of glycoproteins
and glycolipids and modulate a broad spectrum of physiological and pathological …

Common immunological and prognostic features of lung and bladder cancer via smoking‐related genes: PRR11 gene as potential immunotherapeutic target

YX Wang, HX Zhu, L Zhang, JX He, J Bo… - Journal of Cellular …, 2024 - Wiley Online Library
Smoking is a well‐known risk factor for non‐small‐cell lung cancer (NSCLC) and bladder
urothelial carcinoma (BLCA). Despite this, there has been no investigation into a prognostic …

Emerging Roles of Galectin-3 in Pulmonary Diseases

Q Jia, Y Yang, S Yao, X Chen, Z Hu - Lung, 2024 - Springer
Galectin-3 is a multifunctional protein that is involved in various physiological and
pathological events. Emerging evidence suggests that galectin-3 also plays a critical role in …

Repeated intratracheal instillation of whole‐cigarette smoke condensate to assess lung damage in a rat model

J Kim, Y Cho, GJ Oh, HB Park, MJ Yang… - Environmental …, 2024 - Wiley Online Library
Cigarette smoke induces an inflammatory response in the lungs by recruiting inflammatory
cells, leading to lung diseases such as lung cancer, chronic obstructive pulmonary disease …

[HTML][HTML] RUNX transcription factors: biological functions and implications in cancer

X Chen, L Wang, M Yang, W Zhao, J Tu, B Liu… - Clinical and …, 2024 - Springer
Runt-related transcription factors (RUNX) are a family of transcription factors that are
essential for normal and malignant hematopoietic processes. Their most widely recognized …

Sulfur Conversion Pathway-Dependent Production of Endogenous Hydrogen Sulfide Accelerated Trauma-Induced Heterotopic Ossification Through the Ca2+/Erk …

Z Yuan, H Wang, K He, J Li, Z Sun, C Fan… - Available at SSRN … - papers.ssrn.com
AbstractUnveiling of the mechanism involved in the occurrence and development of trauma-
induced heterotopic ossification (tHO) is highly demanding due to current ineffective clinical …