Mitochondria are double-membrane organelles that play a role in ATP synthesis, calcium
homeostasis, oxidation-reduction status, apoptosis, and inflammation. Several human …

Autophagy is an evolutionarily conserved cellular system crucial for cellular homeostasis
that protects cells from a broad range of internal and extracellular stresses. Autophagy …

Fibrosis is a hallmark of progressive kidney diseases. The overexpression of profibrotic
cytokine, namely transforming growth factor β (TGF-β) due to excessive inflammation and …

Ethnopharmacological relevance The prevalence of kidney disease has increased rapidly in
recent years and has emerged as one of the leading causes of mortality worldwide. Natural …

Background and objectives: Oleanolic acid (OA) is a penta-cyclic triterpene with diverse
bioactivities such as anticarcinogenic, antiviral, antimicrobial, hepatoprotective, anti …

The patients with kidney diseases are increasing rapidly all over the world. With the rich
abundance of mitochondria, kidney is an organ with a high consumption of energy. Hence …

Objectives The diuretic and kidney protective effect of the 3-demethyl-2-geranyl-4-
prenylbellidifoline (DGP) were evaluated in rats. Methods The normotensive (NTR) and …

Chronic kidney disease (CKD) with high morbidity and mortality all over the world is
characterized by decreased kidney function, a condition which can result from numerous risk …

Introduction: Chronic kidney disease (CKD) can lead to significant elevation of 1-
deoxysphingolipids (1-deoxySL). The increase of 1-deoxySL in turn can result in …

Rhodiola rosea is a valuable functional medicinal plant widely utilized in China and other
Asian countries for its anti-fatigue, anti-aging, and altitude sickness prevention properties …