Drug toxicity can be the consequence of absence or very poor enzyme activity, especially if
no other metabolic route is available. In the case of reduced enzyme activity, it is …

DAH has been associated with vitamin K deficiency and suggested as potential trigger of
fibrosing interstitial pneumonias. Information on genetic variation might benefit ongoing/new …

We used Drosophila melanogaster to map the genetic basis of naturally occurring variation
in voluntary consumption of cocaine and methamphetamine. We derived an outbred …

Cocaine is an illegal drug; its abuse and toxicity are a public health problem due to its high
morbidity and mortality. Cocaine can affect the cardiovascular, central nervous and …

Background Pulmonary toxicity has been associated with drug use. This is often not
recognized in clinical practice, and underestimated. Objective We aimed to establish …

Opioid overdose (OD) has become a major public health issue in the United States and
throughout the world. Opioid OD is typically defined by exposure to an opioid that results in …

Drugs are serious but underestimated causative agents of interstitial lung disease (ILD).
Both cytotoxic and immune mechanisms may be involved in drug-induced ILD (DI-ILD). We …

Cocaine, an alkaloid extract from a plant, acts as a central nervous system stimulant by
binding and blocking monoamine (dopamine, norepinephrine, epinephrine, and serotonin) …

Cocaine and heroin cause impairment of neural plasticity in the brain including striatum.
This study aimed to identify genes differentially expressed in the striatum of cynomolgus …

Memory is the ability of an individual to record the information and recall it whenever
needed. A complex network of numerous nerve cells and cortex of brain helps us to store …